Does antibiotic choice for the treatment of suspected late-onset sepsis in premature infants determine the risk of developing necrotising enterocolitis? A systematic review.
Sign Up to like & getrecommendations! Published in 2018 at "Early human development"
DOI: 10.1016/j.earlhumdev.2018.06.009
Abstract: BACKGROUND Necrotising enterocolitis (NEC) is a significant cause of infant morbidity and mortality, disproportionately affecting those of extreme prematurity and/or very low birth weight. A number of risk factors have been identified, including an association… read more here.
Keywords: late onset; risk; onset sepsis; risk developing ... See more keywords
Neonatal early-onset infections: Comparing the sensitivity of the neonatal early-onset sepsis calculator to the Dutch and the updated NICE guidelines in an observational cohort of culture-positive cases
Sign Up to like & getrecommendations! Published in 2022 at "EClinicalMedicine"
DOI: 10.1016/j.eclinm.2021.101270
Abstract: Summary Background The early-onset sepsis calculator (EOSC) reduces unnecessary antibiotic treatment in newborns. However, its performance in identifying cases with early-onset disease (EOD) is unclear. We compared the sensitivity of the EOSC to the current… read more here.
Keywords: neonatal early; onset sepsis; grant; nice guidelines ... See more keywords
Evaluation of time to antibiotic administration for suspected late-onset sepsis in the Neonatal Intensive Care Unit: A quality improvement project
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neonatal Nursing"
DOI: 10.1016/j.jnn.2021.03.004
Abstract: Abstract Late-onset sepsis is a significant cause of morbidity and mortality, with mortality increasing by 8–9% for each hour delay in antibiotics. The primary objective of this study is to evaluate the time to antibiotic… read more here.
Keywords: time; sepsis; late onset; onset sepsis ... See more keywords
Family integrated care in single family rooms for preterm infants and late-onset sepsis: a retrospective study and mediation analysis
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Research"
DOI: 10.1038/s41390-020-0875-9
Abstract: Background During hospital stay after birth, preterm infants are susceptible to late-onset sepsis (LOS). Objective To study the effect of family integrated care in single family rooms (SFRs) compared to standard care in open bay… read more here.
Keywords: late onset; onset sepsis; family rooms; family ... See more keywords
Screening for Third-Generation Cephalosporin-Resistant Bacteria Reduces the Incidence on Late-Onset Sepsis and Antibiotic use in Neonates.
Sign Up to like & getrecommendations! Published in 2020 at "Klinische Padiatrie"
DOI: 10.1055/a-1128-0524
Abstract: BACKGROUND The extensive use of antibiotics is reflected by an increasing prevalence of infections with multidrug-resistant bacteria, including third-generation cephalosporin-resistant bacteria (3GCRB). For neonatal intensive care units screening and enhanced barrier precautions are recommended to… read more here.
Keywords: late onset; onset sepsis; use; der ... See more keywords
Epidemiology of Hospital-Onset Versus Community-Onset Sepsis in U.S. Hospitals and Association With Mortality: A Retrospective Analysis Using Electronic Clinical Data.
Sign Up to like & getrecommendations! Published in 2019 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000003817
Abstract: OBJECTIVES Prior studies have reported that hospital-onset sepsis is associated with higher mortality rates than community-onset sepsis. Most studies, however, have used inconsistent case-finding methods and applied limited risk-adjustment for potential confounders. We used consistent… read more here.
Keywords: sepsis; onset sepsis; community onset; hospital onset ... See more keywords
Treprostinil for persistent pulmonary hypertension of the newborn, with early onset sepsis in preterm infant
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DOI: 10.1097/md.0000000000007303
Abstract: Rationale: Persistent pulmonary hypertension of the newborn (PPHN) is a syndrome of failed circulatory adaptation at birth with persisting increased pulmonary vascular resistance that is associated with high mortality rates especially in preterm infants. Patient… read more here.
Keywords: persistent pulmonary; early onset; pulmonary hypertension; onset sepsis ... See more keywords
Strategies to improve antibiotic use in the neonatal ICU
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DOI: 10.1097/mop.0000000000000716
Abstract: Purpose of review Neonates are at a high risk of infection and may have nonspecific signs of sepsis. Accordingly, they are heavily exposed to antimicrobials. Neonates are also uniquely at risk of both short-term and… read more here.
Keywords: onset sepsis; antibiotic use; strategies improve; improve antibiotic ... See more keywords
Serial clinical observation for management of newborns at risk of early-onset sepsis.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000000864
Abstract: PURPOSE OF REVIEW Current management approaches for asymptomatic neonates at risk of early onset sepsis remain controversial. Strategies based entirely on clinical observation (SCO, serial clinical observation) have gained consensus. RECENT FINDINGS We briefly compare… read more here.
Keywords: clinical observation; onset sepsis; early onset; risk early ... See more keywords
Multiplex Cytokine Profiling Identifies Interleukin-27 as a Novel Biomarker For Neonatal Early Onset Sepsis
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DOI: 10.1097/shk.0000000000000753
Abstract: Background: Early onset sepsis (EOS) remains a major cause of mortality and morbidity in neonates, and traditional clinical markers effective for adults are less effective in these patients. This study aimed to assess the value… read more here.
Keywords: sepsis; early onset; onset sepsis; cytokine profiling ... See more keywords
Clinical utility of a model‐based amoxicillin dosage regimen in neonates with early‐onset sepsis
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.15521
Abstract: Early‐onset sepsis (EOS) is one of the most significant causes of morbidity and mortality in neonates. Currently, amoxicillin is empirically used to treat neonates with EOS. However, data on its effectiveness in neonates with EOS… read more here.
Keywords: early onset; based amoxicillin; model; dosage regimen ... See more keywords