Mycophenolate Mofetil and New-Onset Systemic Lupus Erythematosus
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2024.32131
Abstract: Key Points Question What are the efficacy and safety of mycophenolate mofetil (MMF) in patients with new-onset systemic lupus erythematosus (SLE), with high titers of anti–double-stranded DNA antibody, and without major organ involvement? Findings This… read more here.
Keywords: new onset; onset systemic; mycophenolate mofetil; systemic lupus ... See more keywords
Childhood-Onset Systemic Lupus Erythematosus (cSLE): An International Perspective
Sign Up to like & getrecommendations! Published in 2024 at "Current Allergy and Asthma Reports"
DOI: 10.1007/s11882-024-01169-3
Abstract: Childhood-onset systemic lupus erythematosus (cSLE) is a severe and potentially life-threatening chronic autoimmune disease. cSLE is more aggressive and has poorer outcomes than adult-onset disease. The global burden of cSLE is poorly understood, with most… read more here.
Keywords: onset systemic; erythematosus csle; care; systemic lupus ... See more keywords
Chorioretinal Findings in a Patient with New-Onset Systemic Lupus Erythematosus and Antiphospholipid Syndrome after Stillbirth Associated with Pre eclampsia.
Sign Up to like & getrecommendations! Published in 2023 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2023.2168699
Abstract: PURPOSE To describe chorioretinal findings in a patient with new-onset systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) after a stillbirth associated with preeclampsia. STUDY DESIGN Case report. RESULTS We report a patient with new-onset… read more here.
Keywords: patient new; new onset; systemic lupus; lupus erythematosus ... See more keywords
Co-presentation of adult-onset systemic lupus erythematosus and nemaline myopathy.
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology"
DOI: 10.1093/rheumatology/kex252
Abstract: Complete List of Authors: Hindocha, Akshay; Northwick Park Hospital, Emergency Medicine Klimiuk, Peter; Pennine MSK Partnership Ltd, Pennine MSK Partnership Ltd Roberts, Mark; Neurology, Salford Royal Pal, Piyali; Salford Royal NHS Foundation Trust, Department of… read more here.
Keywords: medicine; adult onset; centre; onset systemic ... See more keywords
Clinical efficacy and safety of sirolimus in childhood-onset systemic lupus erythematosus in real world
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DOI: 10.1097/md.0000000000031551
Abstract: To investigate the effectiveness and safety of sirolimus in childhood-onset systemic lupus erythematosus in a real world. This is a retrospective real world clinical study. All childhood-onset systemic lupus erythematosus patients treated with sirolimus in… read more here.
Keywords: systemic lupus; childhood onset; lupus erythematosus; onset systemic ... See more keywords
Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/ard-2022-222795
Abstract: Objectives Families that contain multiple siblings affected with childhood onset of systemic lupus erythematosus (SLE) likely have strong genetic predispositions. We performed whole exome sequencing (WES) to identify familial rare risk variants and to assess… read more here.
Keywords: loss function; systemic lupus; childhood onset; lupus erythematosus ... See more keywords
Biallelic NPR1 loss of function variants are responsible for neonatal systemic hypertension
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Genetics"
DOI: 10.1136/jmg-2023-109176
Abstract: Background Early-onset isolated systemic hypertension is a rare condition of unknown genetic origin. Renovascular, renal parenchymal diseases or aortic coarctation are the most common causes of secondary systemic hypertension in younger children and neonates. We… read more here.
Keywords: loss function; hypertension; early onset; systemic hypertension ... See more keywords
The effectiveness and safety of biological therapeutics in juvenile-onset systemic lupus erythematosus (JSLE): a systematic review
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DOI: 10.1177/0961203318804879
Abstract: Objective To systematically review and summarize the available literature regarding the effectiveness and safety of biologics in the treatment of juvenile-onset systemic lupus erythematosus. Methods PubMed was systematically searched for relevant literature (2012–2017 inclusive) using… read more here.
Keywords: systemic lupus; lupus erythematosus; onset systemic; lupus ... See more keywords
Munchausen by proxy syndrome mimicking childhood-onset systemic lupus erythematosus
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DOI: 10.1177/0961203318821156
Abstract: Childhood-onset systemic lupus erythematosus (cSLE) is a chronic inflammatory multisystem autoimmune disease that requires multiple differential diagnoses. Munchausen by proxy syndrome (MBPS) is a form of child abuse, where a caregiver intentionally creates a medical… read more here.
Keywords: proxy syndrome; systemic lupus; lupus erythematosus; onset systemic ... See more keywords
Safety and efficacy of telitacicept in refractory childhood-onset systemic lupus erythematosus: A self-controlled before–after trial
Sign Up to like & getrecommendations! Published in 2022 at "Lupus"
DOI: 10.1177/09612033221097812
Abstract: Objective To observe the efficacy and safety of telitacicept in refractory childhood-onset systemic lupus erythematosus (cSLE). Methods A self-controlled before–after trial. Children with active SLE, aged 5–18 years, who cannot tolerate side effects of glucocorticoid,… read more here.
Keywords: telitacicept refractory; refractory childhood; efficacy; childhood onset ... See more keywords
A 5–year follow-up of pulmonary function tests in childhood-onset systemic lupus erythematosus: a single-center retrospective study
Sign Up to like & getrecommendations! Published in 2023 at "Lupus"
DOI: 10.1177/09612033231163831
Abstract: Significance Pulmonary involvement in childhood-onset systemic lupus erythematosus (cSLE), contributes to significant morbidity and mortality. Manifestations include chronic interstitial pneumonitis, pneumonia, pleuritis, alveolar hemorrhage, and shrinking lung syndrome. However, many patients can be asymptomatic from… read more here.
Keywords: pulmonary function; systemic lupus; childhood onset; lupus erythematosus ... See more keywords