VPS34 Governs Oocyte Developmental Competence by Regulating Mito/Autophagy: A Novel Insight into the Significance of RAB7 Activity and Its Subcellular Location
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DOI: 10.1002/advs.202308823
Abstract: Asynchronous nuclear and cytoplasmic maturation in human oocytes is believed to cause morphological anomalies after controlled ovarian hyperstimulation. Vacuolar protein sorting 34 (VPS34) is renowned for its pivotal role in regulating autophagy and endocytic trafficking.… read more here.
Keywords: activity subcellular; governs oocyte; oocyte developmental; vps34 ... See more keywords
Transporting cumulus complexes using novel meiotic arresting conditions permits maintenance of oocyte developmental competence
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DOI: 10.1007/s10815-017-0958-7
Abstract: PurposeThe aim of this study is to evaluate the effect of a novel bovine cumulus oocyte complex (COC) shipping media designed to arrest meiotic resumption during transport on meiotic arrest, as well as meiotic resumption,… read more here.
Keywords: oocyte developmental; cumulus; control; developmental competence ... See more keywords
Cumulus cell pappalysin-1, luteinizing hormone/choriogonadotropin receptor, amphiregulin and hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 mRNA levels associate with oocyte developmental competence and embryo outcomes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-019-01489-8
Abstract: PurposeTo determine whether a selected set of mRNA biomarkers expressed in individual cumulus granulosa cell (CC) masses show association with oocyte developmental competence, embryo ploidy status, and embryo outcomes.MethodsThis prospective observational cohort pilot study assessed… read more here.
Keywords: oocyte developmental; delta; mrna levels; embryo ... See more keywords
P-230 Use of a novel in vivo biosensor to rapidly determine oocyte developmental competence
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DOI: 10.1093/humrep/deae108.600
Abstract: Can a novel in vivo biosensor (IVOS) rapidly determine oocyte developmental competence? Data collected with the IVOS biosensor can be used to determine oocyte developmental competence, observed as blastocyst development after in vitro embryo production.… read more here.
Keywords: blastocyst; developmental competence; biosensor; ivos ... See more keywords
Extracellular vesicles secreted by cumulus cells contain microRNAs that are potential regulatory factors of mouse oocyte developmental competence
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DOI: 10.1093/molehr/gaae019
Abstract: Abstract The role of cumulus cells (CCs) in the acquisition of oocyte developmental competence is not yet fully understood. In a previous study, we matured cumulus-denuded fully-grown mouse oocytes to metaphase II (MII) on a… read more here.
Keywords: extracellular vesicles; developmental competence; ccs; oocyte developmental ... See more keywords
Intrafollicular fibroblast growth factor 13 in polycystic ovary syndrome: relationship with androgen levels and oocyte developmental competence
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DOI: 10.1186/s13048-018-0455-3
Abstract: BackgroundFibroblast growth factor 13 (FGF13) is one of the most highly expressed FGF family members in adult mouse ovary. However, its precise roles in ovarian function remain largely unknown. We sought to evaluate the associations… read more here.
Keywords: oocyte developmental; polycystic ovary; pcos; growth factor ... See more keywords