Selective Translation of Maternal mRNA by eIF4E1B Controls Oocyte to Embryo Transition
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205500
Abstract: Maternal messenger ribonucleic acids (mRNAs) are driven by a highly orchestrated scheme of recruitment to polysomes and translational activation. However, selecting and regulating individual mRNAs for the translation from a competitive pool of mRNAs are… read more here.
Keywords: embryo transition; translation; mrna; selective translation ... See more keywords
Revisiting the early days of oocyte and embryo donation: relevance to contemporary clinical practice.
Sign Up to like & getrecommendations! Published in 2018 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2018.09.005
Abstract: Oocyte and embryo donation have evolved significantly since they were first introduced to treat human infertility nearly four decades ago. Social, ethical, and regulatory challenges to oocyte and embryo donation have generated controversy and invited… read more here.
Keywords: revisiting early; days oocyte; embryo donation; oocyte embryo ... See more keywords
Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1807918115
Abstract: Significance Reactive oxygen species (ROS) increase with age and have been shown to negatively impact age-related diseases. However, the physiological roles they might play in development have not been extensively characterized. Here, we show that… read more here.
Keywords: state; embryo transition; transition; oocyte embryo ... See more keywords
Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1009390
Abstract: Post-transcriptional regulation of gene expression is crucial during the oocyte-to-embryo transition, a highly dynamic process characterized by the absence of nuclear transcription. Thus, changes to the RNA content are solely dependent on RNA degradation. Although… read more here.
Keywords: embryo transition; ski7; rna; oocyte embryo ... See more keywords
The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF
Sign Up to like & getrecommendations! Published in 2020 at "Endocrine Connections"
DOI: 10.1530/ec-20-0135
Abstract: The negative impact of endocrine-disrupting pesticides on human fertility is now a key issue in reproductive health. There are much fewer literature data about the impact of pesticide exposure on women than on men and… read more here.
Keywords: chemicals oocyte; endocrine disruptor; disruptor chemicals; oocyte embryo ... See more keywords