Epidermal growth factor and three-dimensional scaffolds provide conducive environment for differentiation of mouse embryonic stem cells into oocyte-like cells.
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DOI: 10.1002/cbin.11391
Abstract: Three-dimensional (3D) culture provides a biomimicry of the naive microenvironment that can support cell proliferation, differentiation and regeneration. Some growth factors, such as epidermal growth factor (EGF), facilitate normal meiosis during oocyte maturation in vivo.… read more here.
Keywords: growth factor; oocyte like; differentiation; mouse embryonic ... See more keywords
In vitro differentiation of human oocyte-like cells from oogonial stem cells: single-cell isolation and molecular characterization
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DOI: 10.1093/humrep/dex377
Abstract: STUDY QUESTION Are the large cells derived from cultured DEAD box polypeptide 4 (DDX4)-positive oogonial stem cells (OSCs), isolated from the ovarian cortex of non-menopausal and menopausal women, oocyte-like cells? SUMMARY ANSWER Under appropriate culture… read more here.
Keywords: menopausal women; like cells; non menopausal; oocyte like ... See more keywords