High-dose synthetic phenolic antioxidant propyl gallate impairs mouse oocyte meiotic maturation through inducing mitochondrial dysfunction and DNA damage.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23807
Abstract: Propyl gallate (PG) is one of the most widely used antioxidants in food products, cosmetics and pharmaceutical industries. Increased research has suggested that exposure to PG influences reproductive health in humans and animals. However, until… read more here.
Keywords: oocyte meiotic; meiotic maturation; dna damage; propyl gallate ... See more keywords
Glutathione alleviates the cadmium exposure-caused porcine oocyte meiotic defects via eliminating the excessive ROS.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental pollution"
DOI: 10.1016/j.envpol.2019.113194
Abstract: Heavy metal cadmium (Cd) is a widespread environmental contaminant with a potential toxicity that might adversely influence the health of experimental animals and humans. It has been known that Cd might accumulate in vertebrates for… read more here.
Keywords: exposure; oocyte meiotic; exposure caused; glutathione alleviates ... See more keywords
Mitochondrial E3 ubiquitin ligase MARCH5 is required for mouse oocyte meiotic maturation
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac215
Abstract: Abstract As the most abundant organelles in oocytes, mitochondria play an important role in maintaining oocyte quality. Here, we report that March5, encoding a mitochondrial ubiquitin ligase that promotes mitochondrial elongation, plays a critical role… read more here.
Keywords: maturation; meiotic maturation; mitochondrial ubiquitin; oocyte meiotic ... See more keywords
Cyclins regulating oocyte meiotic cell cycle progressionâ€
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioz143
Abstract: Abstract Oocyte meiotic maturation is a vital and final process in oogenesis. Unlike somatic cells, the oocyte needs to undergo two continuous meiotic divisions (meiosis I and meiosis II) to become a haploid gamete. Notably,… read more here.
Keywords: cyclins regulating; meiotic progression; oocyte meiotic; regulating oocyte ... See more keywords
Spatiotemporal regulation of maternal mRNAs during vertebrate oocyte meiotic maturation
Sign Up to like & getrecommendations! Published in 2023 at "Biological Reviews"
DOI: 10.1111/brv.12937
Abstract: Vertebrate oocytes face a particular challenge concerning the regulation of gene expression during meiotic maturation. Global transcription becomes quiescent in fully grown oocytes, remains halted throughout maturation and fertilization, and only resumes upon embryonic genome… read more here.
Keywords: maturation; meiotic maturation; maternal mrnas; vertebrate ... See more keywords
28: CAN PHTHALATES DISRUPT OOCYTE MEIOTIC MATURATION IN MOUSE MODEL?
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Open"
DOI: 10.1136/bmjopen-2016-015415.28
Abstract: Background and aims: Phthalates, which are commonly used to render plastics into soft and flexible materials, have also determined as developmental and reproductive toxicants in human and animals. The purpose of this study was to… read more here.
Keywords: oocytes retrieved; meiotic maturation; oocyte meiotic; maturation mouse ... See more keywords
C. elegans XMAP215/ZYG-9 and TACC/TAC-1 act at multiple times during oocyte meiotic spindle assembly and promote both spindle pole coalescence and stability
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Genetics"
DOI: 10.1371/journal.pgen.1010363
Abstract: The conserved two-component XMAP215/TACC modulator of microtubule stability is required in multiple animal phyla for acentrosomal spindle assembly during oocyte meiotic cell division. In C. elegans, XMAP215/zyg-9 and TACC/tac-1 mutant oocytes exhibit multiple and indistinguishable… read more here.
Keywords: zyg; oocyte meiotic; tac; spindle assembly ... See more keywords
SHP2 Nuclear/Cytoplasmic Trafficking in Granulosa Cells Is Essential for Oocyte Meiotic Resumption and Maturation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.611503
Abstract: Src-homology-2-containing phosphotyrosine phosphatase (SHP2), a classic cytoplasmic protein and a major regulator of receptor tyrosine kinases and G protein-coupled receptors, plays a significant role in preimplantation embryo development. In this study, we deciphered the role… read more here.
Keywords: nppc npr2; shp2; nuclear cytoplasmic; oocyte meiotic ... See more keywords
Intrafollicular Retinoic Acid Signaling Is Important for Luteinizing Hormone-Induced Oocyte Meiotic Resumption
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14040946
Abstract: It has been clear that retinoic acid (RA), the most active vitamin A (VA) derivative, plays a central role in governing oocyte meiosis initiation. However, it has not been functionally determined if RA participates in… read more here.
Keywords: resumption; meiotic resumption; oocyte meiotic; retinoic acid ... See more keywords