Inosine RNA modifications are enriched at the codon wobble position in mouse oocytes and eggs†
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioz130
Abstract: Abstract Mammalian oocytes and eggs are transcriptionally quiescent and depend on post-transcriptional mechanisms for proper maturation. Post-transcriptional mRNA modifications comprise an important regulatory mechanism that can alter protein and miRNA recognition sites, splicing, stability, secondary… read more here.
Keywords: inosine; oocytes eggs; enriched codon; wobble position ... See more keywords
Deletion of TRPV3 and CaV3.2 T-type channels in mice undermines fertility and Ca2+ homeostasis in oocytes and eggs.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.257956
Abstract: Calcium (Ca2+) influx during oocyte maturation and after sperm entry is necessary to fill the internal Ca2+ stores and for complete egg activation. We knocked out the transient receptor potential vanilloid member 3 (TRPV3) and… read more here.
Keywords: type; trpv3 cav3; oocytes eggs; ca2 ... See more keywords