Age-related accumulation of de novo mitochondrial mutations in mammalian oocytes and somatic tissues
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DOI: 10.1371/journal.pbio.3000745
Abstract: Mutations create genetic variation for other evolutionary forces to operate on and cause numerous genetic diseases. Nevertheless, how de novo mutations arise remains poorly understood. Progress in the area is hindered by the fact that… read more here.
Keywords: accumulation; oocytes somatic; novo mutations; duplex sequencing ... See more keywords