Articles with "opb 51602" as a keyword



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STAT3 Inhibitor OPB-51602 Is Cytotoxic to Tumor Cells Through Inhibition of Complex I and ROS Induction

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Published in 2020 at "iScience"

DOI: 10.1016/j.isci.2020.101822

Abstract: Summary STAT3 is a transcription factor involved in several cellular activities including inflammation, proliferation, and survival, but it also plays a non-transcriptional role in modulating mitochondrial metabolism. Given its diverse functions in human cancers, it… read more here.

Keywords: inhibitor; opb 51602; stat3; ros ... See more keywords