Diversity in kinetics correlated with structure in nano body-stabilized LacY
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DOI: 10.1371/journal.pone.0232846
Abstract: The structure of lactose permease, stabilized in a periplasmic open conformation by two Gly to Trp replacements (LacYww) and complexed with a nanobody directed against this conformation, provides the highest resolution structure of the symporter.… read more here.
Keywords: nanobody; open conformation; structure; lacy ... See more keywords
Phosphomimetic S207D Lysyl–tRNA Synthetase Binds HIV-1 5′UTR in an Open Conformation and Increases RNA Dynamics
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DOI: 10.3390/v14071556
Abstract: Interactions between lysyl–tRNA synthetase (LysRS) and HIV-1 Gag facilitate selective packaging of the HIV-1 reverse transcription primer, tRNALys3. During HIV-1 infection, LysRS is phosphorylated at S207, released from a multi-aminoacyl–tRNA synthetase complex and packaged into… read more here.
Keywords: trna synthetase; phosphomimetic s207d; lysyl trna; synthetase ... See more keywords
Computer modelling reveals new conformers of the ATP binding loop of Na+/K+-ATPase involved in the transphosphorylation process of the sodium pump
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DOI: 10.7717/peerj.3087
Abstract: Hydrolysis of ATP by Na+/K+-ATPase, a P-Type ATPase, catalyzing active Na+ and K+ transport through cellular membranes leads transiently to a phosphorylation of its catalytical α-subunit. Surprisingly, three-dimensional molecular structure analysis of P-type ATPases reveals… read more here.
Keywords: atpase; atp binding; open conformation; loop ... See more keywords