Articles with "open targets" as a keyword



The next-generation Open Targets Platform: reimagined, redesigned, rebuilt

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Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkac1046

Abstract: Abstract The Open Targets Platform (https://platform.opentargets.org/) is an open source resource to systematically assist drug target identification and prioritisation using publicly available data. Since our last update, we have reimagined, redesigned, and rebuilt the Platform… read more here.

Keywords: redesigned rebuilt; open targets; targets platform; reimagined redesigned ... See more keywords

Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery

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Published in 2024 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkae1128

Abstract: Abstract The Open Targets Platform (https://platform.opentargets.org) is a unique, open-source, publicly-available knowledge base providing data and tooling for systematic drug target identification, annotation, and prioritisation. Since our last report, we have expanded the scope of… read more here.

Keywords: targets platform; open targets; therapeutic hypotheses; drug discovery ... See more keywords

Identification of Potential Therapeutic Targets on the Level of DNA/mRNAs, Proteins and Metabolites: A Systematic Mapping Review of Scientific Texts’ Fragments from Open Targets

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Published in 2023 at "Current Issues in Molecular Biology"

DOI: 10.3390/cimb45040223

Abstract: Database records contain useful information, which is readily available, but, unfortunately, limited compared to the source (publications). Our study reviewed the text fragments supporting the association between the biological macromolecules and diseases from Open Targets… read more here.

Keywords: open targets; identification potential; level dna; proteins metabolites ... See more keywords