Computational insight into the mechanism and origin of high regioselectivity in the ring-opening cyclization of spirocyclopropanes with stabilized sulfonium ylides by the DFT
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DOI: 10.1007/s00894-020-04522-1
Abstract: Chromanes with high bioactivity play an important role in nature, and cyclization reactions of cyclopropanes with sulfonium ylides to form chromane skeletons have attracted great attention of scientists. The mechanism as well as origins of… read more here.
Keywords: ring opening; regioselectivity; cyclization; opening cyclization ... See more keywords
One-Pot Acid-Catalyzed Ring-Opening/Cyclization/Oxidation of Aziridines with N-Tosylhydrazones: Access to 1,2,4-Triazines.
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DOI: 10.1021/acs.orglett.7b00101
Abstract: A new, three-step, telescoped reaction sequence for the regioselective conversion of N-tosyl hydrazones and aziridines to 3,6-disubstituted and 3,5,6-trisubstituted 1,2,4-triazines is described. The process involves an efficient nucleophilic ring opening of the aziridine, giving access… read more here.
Keywords: ring opening; one pot; opening cyclization; cyclization oxidation ... See more keywords
Tandem Oxidative Ring-Opening/Cyclization Reaction in Seconds in Open Atmosphere for the Synthesis of 1-Tetralones in Water-Acetonitrile.
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DOI: 10.1021/acs.orglett.8b03246
Abstract: A mild and practical tandem oxidative ring-opening/cyclization reaction mediated by Ce4+ for the synthesis of 1-tetralones is presented. This rapid transformation was completed within 30 s and conducted in an open reactor at 0 °C… read more here.
Keywords: tandem oxidative; ring opening; oxidative ring; cyclization reaction ... See more keywords
Molecular Mechanism and Solvation Effect of Supramolecular Catalysis in a Synthetic Cavitand Receptor with an Inwardly Directed Carboxylic Acid for Ring-Opening Cyclization of Epoxy Alcohols
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DOI: 10.1021/acscatal.8b03256
Abstract: Supramolecular catalysis has become a hot topic in chemistry. To understand the origin of supramolecular catalysis, the catalytic mechanism of a synthetic cavitand receptor with an inwardly directed carboxylic acid for ring-opening cyclization of epoxy… read more here.
Keywords: ring opening; carboxylic acid; catalysis; opening cyclization ... See more keywords
Oxidative radical ring-opening/cyclization of cyclopropane derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.15.23
Abstract: The ring-opening/cyclization of cyclopropane derivatives has drawn great attention in the past several decades. In this review, recent efforts in the development of oxidative radical ring-opening/cyclization of cyclopropane derivatives, including methylenecyclopropanes, cyclopropyl olefins and cyclopropanols,… read more here.
Keywords: cyclization cyclopropane; ring opening; cyclopropane derivatives; opening cyclization ... See more keywords