Ring-opening Fluorination of Carbo/Heterocycles and Aromatics: Construction of Complex and Diverse Fluorine-containing Molecules.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical record"
DOI: 10.1002/tcr.202200281
Abstract: Fluorine-containing molecules have attracted much attention in medicinal, agrochemical, and materials sciences because they offer unique physical and biological properties. Therefore, many efficient fluorination reactions have been developed over the years. Recent advancements in fluorination… read more here.
Keywords: containing molecules; fluorine; fluorine containing; ring opening ... See more keywords
Ring-opening fluorination of cyclopropylmethanols and cycloprpanecarbardehydes with diethylaminosulfur trifluoride
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2020.152655
Abstract: Abstract The reaction of cyclopropylmethanols bearing aromatic substituents on their cyclopropane rings with diethylaminosulfur trifluoride (DAST) effectively caused ring-opening fluorination to produce homoallylic fluorides. This reaction proceeded via a carbocation intermediate. DAST reacted with cyclopropanecarbaldehydes… read more here.
Keywords: ring opening; fluorination cyclopropylmethanols; diethylaminosulfur trifluoride; cyclopropylmethanols cycloprpanecarbardehydes ... See more keywords
Ring-Opening Fluorination of Isoxazoles.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01149
Abstract: A ring-opening fluorination of isoxazoles has been developed. Upon treatment of isoxazoles with an electrophilic fluorinating agent (Selectfluor), fluorination followed by deprotonation leads to tertiary fluorinated carbonyl compounds. This method features mild reaction conditions, good… read more here.
Keywords: opening fluorination; fluorination isoxazoles; ring opening; fluorination ... See more keywords