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Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03529
Abstract: A chiral phosphoric acid-catalyzed ring-opening of meso-epoxides was developed. A range of 2-azabicyclo[2.2.1]heptanes were obtained in high yields with excellent enantioselectivities. In addition, the hydroxyl and amide groups in the products provided handles for further…
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Keywords:
opening meso;
catalyzed ring;
meso epoxides;
azabicyclo heptanes ... See more keywords