Thiophene ring-opening reactions. Direct access to the synthesis of 1,3,4-thiadiazoline-(condenced) pyridone hybrids
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2021.131957
Abstract: Abstract The reaction of N’-(aryl)benzothiohydrazides with 2-chloro-7-cyclopropyl-3-nitro-4-oxothieno[2,3-b]pyridine-5-carboxylic ester/acid in the presence of triethylamine furnished, upon addition of iodomethane, the respective 1,3,4-thiadiazoline-(6-methylthio-4-oxopyridine) hybrids. Interestingly, the reaction of thiohydrazides with 4-oxothieno[2,3-b]pyridines incorporating N1-(2’-halogeno-5’-nitrophenyl) entities generated 1,3-thiazoline ring… read more here.
Keywords: opening reactions; thiadiazoline; thiophene ring; direct access ... See more keywords
Rhodium-Catalyzed Asymmetric Arylative Ring-Opening Reactions of Heterobicyclic Alkenes with Anilines.
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DOI: 10.1021/acs.orglett.7b03941
Abstract: Asymmetric arylative ring-opening reactions of heterobicyclic alkenes with anilines have been reported for the first time. A wide range of heterobicyclic alkenes, including azabenzonorbornadienes and oxabenzonorbornadienes, were well tolerated in the reaction with various anilines,… read more here.
Keywords: ring opening; heterobicyclic alkenes; arylative ring; asymmetric arylative ... See more keywords
Ring opening reactions of heterocycles with selenium and tellurium nucleophiles
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DOI: 10.1039/c9nj02320h
Abstract: An overview of the preparation and synthetic potentialities of functionalized organoselenium and organotellurium compounds is presented. read more here.
Keywords: heterocycles selenium; selenium tellurium; reactions heterocycles; tellurium nucleophiles ... See more keywords
Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones
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DOI: 10.1039/d2ra08257h
Abstract: Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones have been established for the synthesis of enantioenriched γ-hydroxybutyric acid derivatives in the presence of Cu(ii)/trisoxazoline catalyst. These reactions offered the desired products in 70% to 93%… read more here.
Keywords: acceptor cyclopropanes; opening reactions; donor acceptor; ring opening ... See more keywords
Ring expansion/ opening reactions of epoxy ene-amides: Access to azabicyclononene, tetrahydropyridine and tetrazole scaffolds
Sign Up to like & getrecommendations! Published in 2023 at "New Journal of Chemistry"
DOI: 10.1039/d3nj00529a
Abstract: Ene-sulfonamides, obtained from epoxy (terminal as well as internal) benzenesulfonamide and substituted chloro-acrylaldehydes, undergo Lewis acid (BF3.OEt2) catalysed cyclisation to afford azabicyclononene, tetrahydropyridinyl benzoate or tetrahydropyridine-carbaldehyde scaffolds depending on the... read more here.
Keywords: ene; opening reactions; epoxy ene; expansion opening ... See more keywords
Alkylative Aziridine Ring-Opening Reactions
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DOI: 10.3390/molecules26061703
Abstract: In this study, the highly strained three-membered aziridine ring was successfully activated as the aziridinium ion by alkylation of the ring nitrogen with a methyl, ethyl or allyl group, which was followed by ring opening… read more here.
Keywords: aziridine ring; ring opening; opening reactions; alkylative aziridine ... See more keywords
Acid-catalyzed ring-opening reactions of a cyclopropanated 3-aza-2-oxabicyclo[2.2.1]hept-5-ene with alcohols
Sign Up to like & getrecommendations! Published in 2017 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.13.281
Abstract: The acid-catalyzed ring-opening reactions of a cyclopropanated 3-aza-2-oxabicylic alkene using alcohol nucleophiles were investigated. Although this acid-catalyzed ring-opening reaction did not cleave the cyclopropane unit as planned, this represent the first examples of ring-openings of… read more here.
Keywords: ring opening; cyclopropanated aza; reactions cyclopropanated; opening reactions ... See more keywords