Catalytic Asymmetric Ring Opening Reactions of Vinylcyclopropanes
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202301225
Abstract: Vinylcyclopropanes (VCPs) are important building blocks with multifaceted reactivity. Catalytic asymmetric ring opening of vinylcyclopropanes is a highly efficient process to access valuable chiral molecules with diverse functionalities that can be further functionalized for a… read more here.
Keywords: chemistry; asymmetric ring; ring opening; reactions vinylcyclopropanes ... See more keywords
Highly efficient anionic ring-opening reactions of epoxide triggered by phosphide
Sign Up to like & getrecommendations! Published in 2024 at "Polymer Bulletin"
DOI: 10.1007/s00289-024-05256-3
Abstract: Potassium diphenyl phosphide (KPPh2), which forms a highly nucleophilic phosphide anion, was used as an initiator for the anionic ring-opening polymerization of glycidyl phenyl ether (GPE). GPE was selected as a model compound for the… read more here.
Keywords: efficient anionic; reactions epoxide; ring opening; highly efficient ... See more keywords
Thiophene ring-opening reactions. Direct access to the synthesis of 1,3,4-thiadiazoline-(condenced) pyridone hybrids
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2021.131957
Abstract: Abstract The reaction of N’-(aryl)benzothiohydrazides with 2-chloro-7-cyclopropyl-3-nitro-4-oxothieno[2,3-b]pyridine-5-carboxylic ester/acid in the presence of triethylamine furnished, upon addition of iodomethane, the respective 1,3,4-thiadiazoline-(6-methylthio-4-oxopyridine) hybrids. Interestingly, the reaction of thiohydrazides with 4-oxothieno[2,3-b]pyridines incorporating N1-(2’-halogeno-5’-nitrophenyl) entities generated 1,3-thiazoline ring… read more here.
Keywords: opening reactions; thiadiazoline; thiophene ring; direct access ... See more keywords
Gelation during Ring-Opening Reactions of Cellulosics with Cyclic Anhydrides: Phenomena and Mechanisms
Sign Up to like & getrecommendations! Published in 2024 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.4c01081
Abstract: Cellulose esters are used in Food and Drug Administration-approved oral formulations, including in amorphous solid dispersions (ASDs). Some bear substituents with terminal carboxyl moieties (e.g., hydroxypropyl methyl cellulose acetate succinate (HPMCAS)); these ω-carboxy ester substituents… read more here.
Keywords: cellulose esters; gelation ring; ring opening; cyclic anhydrides ... See more keywords
Origin of Chemoselectivity of Halohydrin Dehalogenase-Catalyzed Epoxide Ring-Opening Reactions
Sign Up to like & getrecommendations! Published in 2024 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.4c00640
Abstract: By performing molecular dynamics (MD), quantum mechanical/molecular mechanical (QM/MM) calculations, and QM cluster calculations, the origin of chemoselectivity of halohydrin dehalogenase (HHDH)-catalyzed ring-opening reactions of epoxide with the nucleophilic reagent NO2- has been explored. Four… read more here.
Keywords: halohydrin dehalogenase; opening reactions; ring opening; chemoselectivity ... See more keywords
Rhodium-Catalyzed Asymmetric Arylative Ring-Opening Reactions of Heterobicyclic Alkenes with Anilines.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.7b03941
Abstract: Asymmetric arylative ring-opening reactions of heterobicyclic alkenes with anilines have been reported for the first time. A wide range of heterobicyclic alkenes, including azabenzonorbornadienes and oxabenzonorbornadienes, were well tolerated in the reaction with various anilines,… read more here.
Keywords: ring opening; heterobicyclic alkenes; arylative ring; asymmetric arylative ... See more keywords
Ring opening reactions of heterocycles with selenium and tellurium nucleophiles
Sign Up to like & getrecommendations! Published in 2019 at "New Journal of Chemistry"
DOI: 10.1039/c9nj02320h
Abstract: An overview of the preparation and synthetic potentialities of functionalized organoselenium and organotellurium compounds is presented. read more here.
Keywords: heterocycles selenium; selenium tellurium; reactions heterocycles; tellurium nucleophiles ... See more keywords
Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones
Sign Up to like & getrecommendations! Published in 2023 at "RSC Advances"
DOI: 10.1039/d2ra08257h
Abstract: Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones have been established for the synthesis of enantioenriched γ-hydroxybutyric acid derivatives in the presence of Cu(ii)/trisoxazoline catalyst. These reactions offered the desired products in 70% to 93%… read more here.
Keywords: acceptor cyclopropanes; opening reactions; donor acceptor; ring opening ... See more keywords
Ring expansion/ opening reactions of epoxy ene-amides: Access to azabicyclononene, tetrahydropyridine and tetrazole scaffolds
Sign Up to like & getrecommendations! Published in 2023 at "New Journal of Chemistry"
DOI: 10.1039/d3nj00529a
Abstract: Ene-sulfonamides, obtained from epoxy (terminal as well as internal) benzenesulfonamide and substituted chloro-acrylaldehydes, undergo Lewis acid (BF3.OEt2) catalysed cyclisation to afford azabicyclononene, tetrahydropyridinyl benzoate or tetrahydropyridine-carbaldehyde scaffolds depending on the... read more here.
Keywords: ene; opening reactions; epoxy ene; expansion opening ... See more keywords
Organocatalysis as an enabling tool for enantioselective ring-opening reactions of cyclopropanes.
Sign Up to like & getrecommendations! Published in 2024 at "Chemical communications"
DOI: 10.1039/d4cc01933d
Abstract: The rich reactivity profile of cyclopropanes has been extensively explored to trigger new organic transformations that enable unusual disconnective approaches to synthesize molecular motifs that are not easily reached through conventional reactions. In particular, the… read more here.
Keywords: enabling tool; organocatalysis enabling; ring opening; tool enantioselective ... See more keywords
Alkylative Aziridine Ring-Opening Reactions
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26061703
Abstract: In this study, the highly strained three-membered aziridine ring was successfully activated as the aziridinium ion by alkylation of the ring nitrogen with a methyl, ethyl or allyl group, which was followed by ring opening… read more here.
Keywords: aziridine ring; ring opening; opening reactions; alkylative aziridine ... See more keywords