Electrophysiological Features of Single Store-Operated Calcium Channels in HEK S4 Cell Line with Stable STIM1 Protein Knockdown
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3795-x
Abstract: An important role in intracellular calcium signaling is played by store-operated channels activated by STIM proteins, calcium sensors of the endoplasmic reticulum. In stable STIM1 knockdown HEK S4 cells, single channels activated by depletion of… read more here.
Keywords: calcium; store operated; stable stim1; operated calcium ... See more keywords
Store-Operated Calcium Entry in Mouse Cardiomyocytes
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-019-04516-x
Abstract: The fluorescent dye fura-2 AM was employed to record activation of Ca2+ entry in response to a decrease in Ca2+ concentration in the endoplasmic reticulum. Using whole-cell voltage clamp technique, we revealed Ca2+ currents with… read more here.
Keywords: store operated; calcium entry; entry mouse; entry ... See more keywords
Abstract C045: RP4010, a small molecule inhibitor of Store-Operated Calcium Entry (SOCE), potentiates activity of Gilteritinib and Cytarabine in preclinical models of AML
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.targ-19-c045
Abstract: Background: Store-operated calcium entry (SOCE) through calcium release activated calcium (CRAC) channels contribute to calcium influx in non-excitable cells. Elevation of cytosolic calcium through SOCE mediates an array of cellular responses including metabolism and gene… read more here.
Keywords: soce; operated calcium; calcium entry; activity ... See more keywords
Insect nephrocyte function is regulated by a store operated calcium entry mechanism controlling endocytosis and Amnionless turnover.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of insect physiology"
DOI: 10.2139/ssrn.4166070
Abstract: Insect nephrocytes are ultrafiltration cells that remove circulating proteins and exogenous toxins from the haemolymph. Experimental disruption of nephrocyte development or function leads to systemic impairment of insect physiology as evidenced by cardiomyopathy, chronic activation… read more here.
Keywords: calcium; function; operated calcium; physiology ... See more keywords
Store-Operated Calcium Channels Are Involved in Spontaneous Slow Calcium Oscillations in Striatal Neurons
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2019.00547
Abstract: The striatum plays an important role in linking cortical activity to basal ganglia output. Striatal neurons exhibit spontaneous slow Ca2+ oscillations that result from Ca2+ release from the endoplasmic reticulum (ER) induced by the mGluR5-IP3R… read more here.
Keywords: store operated; striatal neurons; operated calcium; ca2 ... See more keywords
Editorial: Molecular Components of Store-Operated Calcium Entry in Health and Disease
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DOI: 10.3389/fncel.2021.771138
Abstract: 1 Laboratory of Molecular Biology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland, 2 Institute of Molecular Pathology Biomarkers, University of Extremadura, Badajoz, Spain, Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville,… read more here.
Keywords: molecular components; store operated; components store; editorial molecular ... See more keywords
Structures reveal opening of the store-operated calcium channel Orai
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DOI: 10.7554/elife.36758
Abstract: The store-operated calcium (Ca2+) channel Orai governs Ca2+ influx through the plasma membrane of many non-excitable cells in metazoans. The channel opens in response to the depletion of Ca2+ stored in the endoplasmic reticulum (ER).… read more here.
Keywords: store operated; structures reveal; orai; operated calcium ... See more keywords