The Analysis of Pathological and Serological Findings in the Long-Term Pediatric Liver Transplantation: The Achievement of Clinical Operational Tolerance
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation"
DOI: 10.1097/01.tp.0000543991.95051.81
Abstract: Introduction Clinical operational tolerance can be achieved after liver transplantation in some proportion of selected patients. We have tried to reduce immunosuppression (IS) of the stable out-patient pediatric liver transplant recipients. In this cross-sectional study,… read more here.
Keywords: cni; fibrosis; operational tolerance; tolerance ... See more keywords
Application of Operational Tolerance Signatures Are Limited by Variability and Type of Immunosuppression in Renal Transplant Recipients: A Cross-Sectional Study
Sign Up to like & getrecommendations! Published in 2017 at "Transplantation Direct"
DOI: 10.1097/txd.0000000000000638
Abstract: Background Renal transplant recipients (RTR) frequently develop complications relating to chronic immunosuppression. Identifying RTR who could safely reduce immunosuppression is therefore highly desirable. We hypothesized that “signatures” described in RTR who have stopped immunosuppression but… read more here.
Keywords: cross sectional; operational tolerance; renal transplant; immunosuppression ... See more keywords
An exome-wide study of renal operational tolerance
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.976248
Abstract: Background Renal operational tolerance is a rare and beneficial state of prolonged renal allograft function in the absence of immunosuppression. The underlying mechanisms are unknown. We hypothesized that tolerance might be driven by inherited protein… read more here.
Keywords: exome wide; operational tolerance; tolerance; medicine ... See more keywords
Comparative Analyses of Signature Genes in Acute Rejection and Operational Tolerance
Sign Up to like & getrecommendations! Published in 2017 at "Immune Network"
DOI: 10.4110/in.2017.17.4.237
Abstract: Using biomarkers as prediction tools or therapeutic targets can be a valuable strategy in transplantation. Recent studies identified biomarkers of acute rejection (AR) and operational tolerance (TOL) through the application of meta-analysis. In this study,… read more here.
Keywords: analysis; acute rejection; signature genes; operational tolerance ... See more keywords