Experimental demonstration of operon formation catalyzed by insertion sequence
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac004
Abstract: Abstract Operons are a hallmark of the genomic and regulatory architecture of prokaryotes. However, the mechanism by which two genes placed far apart gradually come close and form operons remains to be elucidated. Here, we… read more here.
Keywords: insertion sequences; insertion; insertion sequence; operon formation ... See more keywords
Conservation of mRNA operon formation in control of the heat shock response in mammalian cells
Sign Up to like & getrecommendations! Published in 2025 at "Science Advances"
DOI: 10.1126/sciadv.adu0315
Abstract: Prokaryotes use polycistronic transcription (operons) to express multiple messenger RNAs (mRNAs) from a single promoter to coexpress functionally related genes. However, how do eukaryotes, which express monocistronic messages, achieve the same regulation? Previously, we demonstrated… read more here.
Keywords: heat; operon formation; shock response; heat shock ... See more keywords