New Classes of Polycationic Compounds as Preservatives for Ophthalmic Formulations
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutical Research"
DOI: 10.1007/s11095-018-2536-9
Abstract: PurposeThe purpose of this research work was to develop new polycationic compounds based on pyridine and piperidine structures with high antimicrobial activities against bacteria and fungi. Furthermore, the compounds should offer a lower toxicity than… read more here.
Keywords: classes polycationic; ophthalmic formulations; high antimicrobial; preservatives ophthalmic ... See more keywords
A validated size exclusion chromatography method coupled with fluorescence detection for rapid quantification of bevacizumab in ophthalmic formulations.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.05.038
Abstract: Bevacizumab is a full-length human monoclonal antibody used to treat various neovascular diseases such as wet age-related macular degeneration (AMD), diabetic eye disease and other problems of the retina. Monthly intravitreal injections of bevacizumab (Avastin®)… read more here.
Keywords: ophthalmic formulations; quantification bevacizumab; method; fluorescence ... See more keywords
Stability Indicating UHPLC-PDA Assay for Simultaneous Determination of Antazoline Hydrochloride and Naphazoline Hydrochloride in Ophthalmic Formulations.
Sign Up to like & getrecommendations! Published in 2017 at "Acta chimica Slovenica"
DOI: 10.17344/acsi.2017.3166
Abstract: In the present study, a newly developed method based on ultrahigh performance liquid chromatography (UHPLC) was optimized for the simultaneous determination of antazoline hydrochloride (ANZ) and naphazoline hydrochloride (NFZ) in ophthalmic formulations. Isocratic separation of… read more here.
Keywords: simultaneous determination; hydrochloride; ophthalmic formulations; determination antazoline ... See more keywords