Reverse engineering and formulation by QBD of olopatadine hydrochloride ophthalmic solution
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DOI: 10.1007/s40005-017-0312-1
Abstract: Reverse engineering of innovator product’s formulation is a cost-effective strategy for accelerating generic product development. The total market share for olopatadine hydrochloride (OLH) ophthalmic solution used as an antihistamine in US is nearly $230 million dollars.… read more here.
Keywords: ophthalmic solution; olopatadine hydrochloride; formulation; reverse engineering ... See more keywords
In Vitro and In-Eye Comparison of Commercial Pilocarpine Ophthalmic Solution and an Optimized, Reformulated Pilocarpine for Presbyopia Treatment
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DOI: 10.1007/s40123-022-00482-2
Abstract: Pilocarpine hydrochloride (pilo) ophthalmic solution has traditionally been used for the treatment of glaucoma, with opportunities to improve the tolerability profile experienced by patients. Pilocarpine hydrochloride ophthalmic solution 1.25% (Vuity™, Allergan, an AbbVie company) was… read more here.
Keywords: formulation; vitro; ophthalmic solution; treatment ... See more keywords
Netarsudil Ophthalmic Solution 0.02%: First Global Approval
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DOI: 10.1007/s40265-018-0877-7
Abstract: Netarsudil ophthalmic solution 0.02% (hereafter referred to as netarsudil 0.02%) [Rhopressa®] is a Rho-associated protein kinase inhibitor that is thought to lower intraocular pressure (IOP) by increasing aqueous humour outflow through the trabecular meshwork. It… read more here.
Keywords: solution first; ophthalmic solution; netarsudil ophthalmic; first global ... See more keywords
New resveratrol micelle formulation for ocular delivery: characterization and in vitro/in vivo evaluation
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DOI: 10.1080/03639045.2020.1828909
Abstract: Abstract Many eye diseases, such as corneal wound healing after injury, involve oxidative stress and inflammatory responses; however, many efficient natural antioxidants (e.g. resveratrol) have limited application in ophthalmology due to their poor solubility, low… read more here.
Keywords: resveratrol micelle; ophthalmic solution; sol res; resveratrol ... See more keywords
Tropicamide ophthalmic solution reduces clozapine-induced sialorrhea: a case report
Sign Up to like & getrecommendations! Published in 2017 at "Psychiatry and Clinical Psychopharmacology"
DOI: 10.1080/24750573.2017.1347601
Abstract: ABSTRACT Clozapine-induced sialorrhea (CIS) is a common, treatment-limiting, and stigmatizing side effect. All systemic agents that are used for CIS may increase clozapine side effects such as blood pressure changes, constipation, or arrhythmias or may… read more here.
Keywords: cis; clozapine induced; ophthalmic solution; effect ... See more keywords
Lotilaner Ophthalmic Solution, 0.25%, for the Treatment of Demodex Blepharitis: Results of a Prospective, Randomized, Vehicle-Controlled, Double-Masked, Pivotal Trial (Saturn-1)
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DOI: 10.1097/ico.0000000000003097
Abstract: Purpose: The purpose of this study was to evaluate the safety and efficacy of lotilaner ophthalmic solution, 0.25%, compared with vehicle for the treatment of Demodex blepharitis. Methods: In this prospective, randomized, controlled, double-masked, phase… read more here.
Keywords: lotilaner ophthalmic; demodex blepharitis; ophthalmic solution; cure ... See more keywords
Frequent self-monitoring of intraocular pressure can determine effectiveness of medications in eyes with normal tension glaucoma: A case report
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DOI: 10.1097/md.0000000000032478
Abstract: Rationale: It is difficult to follow changes in the intraocular pressure (IOP) in glaucomatous eyes comprehensively because of the limited number of outpatient examinations. We report our findings in a case of normal tension glaucoma… read more here.
Keywords: intraocular pressure; frequent self; ophthalmic solution; tension glaucoma ... See more keywords
Effects of 0.02% netarsudil ophthalmic solution on intraocular pressure of normotensive dogs.
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DOI: 10.1111/vop.12736
Abstract: OBJECTIVES To evaluate the effect of QD or BID 0.02% netarsudil ophthalmic solution (Aerie Pharmaceuticals) on intraocular pressure (IOP) in normotensive dogs and to describe any adverse effects. ANIMALS STUDIED Normotensive Labrador retriever dogs were… read more here.
Keywords: intraocular pressure; day dosing; ophthalmic solution; netarsudil ophthalmic ... See more keywords
Hypokalemia associated with topical administration of dorzolamide 2% ophthalmic solution in cats.
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DOI: 10.1111/vop.12773
Abstract: OBJECTIVE To evaluate the effect of dorzolamide 2% ophthalmic solution on serum potassium and other hematologic parameters in cats. MATERIALS AND METHODS Part I: Medical records from a single institution were retrospectively reviewed. Inclusion criteria… read more here.
Keywords: ophthalmic solution; administration dorzolamide; serum potassium; dorzolamide ophthalmic ... See more keywords
Efficacy of perioperative 2% dorzolamide ophthalmic solution for reduction of postoperative ocular hypertension in dogs following routine phacoemulsification surgery: A prospective clinical trial.
Sign Up to like & getrecommendations! Published in 2023 at "Veterinary ophthalmology"
DOI: 10.1111/vop.13109
Abstract: OBJECTIVE To evaluate the efficacy of 2% dorzolamide ophthalmic solution for reduction of postoperative ocular hypertension (POH) following routine phacoemulsification surgery in dogs. ANIMALS STUDIED Thirty one dogs (53 eyes) with naturally occurring cataracts undergoing… read more here.
Keywords: postoperative ocular; surgery; ophthalmic solution; phacoemulsification ... See more keywords
Timolol 0.5% ophthalmic solution influences cardiac function in healthy cats
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DOI: 10.1177/1098612x221083372
Abstract: Objectives The aim of this study was to ascertain the effect of a drop of timolol 0.5% ophthalmic solution on the systolic function of the left ventricle (LV) and left atrium (LA), and to confirm… read more here.
Keywords: timolol ophthalmic; function; ophthalmic solution; healthy cats ... See more keywords