Pharmacodynamics and pharmacokinetics of the novel synthetic opioid, U-47700, in male rats
Sign Up to like & getrecommendations! Published in 2020 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2020.108195
Abstract: Novel synthetic opioids are appearing in recreational drug markets worldwide as adulterants in heroin or ingredients in counterfeit analgesic medications. 3,4-Dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide (U-47700) is an example of a non-fentanyl synthetic opioid linked to overdose deaths. Here,… read more here.
Keywords: opioid 47700; novel synthetic; pharmacokinetics novel; pharmacodynamics pharmacokinetics ... See more keywords
First Case in Italy of Fatal Intoxication Involving the New Opioid U-47700
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00747
Abstract: The drug commonly known as U-47700 is a strong μ-opioid agonist with an approximate potency 7.5 times higher than morphine. It has been available in Europe since 2014, where it is usually sold through the… read more here.
Keywords: opioid 47700; intoxication; blood urine; case ... See more keywords