Increased Avoidance Learning in Chronic Opioid Users.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2025.3271
Abstract: Importance The opioid crisis remains a global public health issue, with poor clinical outcomes, low treatment adherence, and early dropouts being major challenges. These may be driven by a pathological increase in avoidance tendencies in… read more here.
Keywords: addiction; reinforcement; avoidance; increased avoidance ... See more keywords
Home-based delivery of XR-NTX in youth with opioid addiction.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of substance abuse treatment"
DOI: 10.1016/j.jsat.2017.08.007
Abstract: Early experience with relapse prevention medications in the treatment of opioid addiction in youth has been positive, but barriers to effectiveness and broader adoption have included problems with adherence and retention, and lack of evidence… read more here.
Keywords: home; home based; treatment; delivery ... See more keywords
Aquaporin-4 deletion attenuates opioid-induced addictive behaviours associated with dopamine levels in nucleus accumbens
Sign Up to like & getrecommendations! Published in 2022 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2022.108986
Abstract: There is a lack of safe and effective non-opioid medications for the treatment of opioid addiction. Aquaporin-4 (AQP4), a water channel protein expressed in astrocytes, regulates the progression of neurological diseases. Our previous work demonstrated… read more here.
Keywords: dopamine; mice; opioid induced; opioid addiction ... See more keywords
Effects of craving on opioid use are attenuated after pain coping counseling in adults with chronic pain and prescription opioid addiction.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of consulting and clinical psychology"
DOI: 10.1037/ccp0000399
Abstract: OBJECTIVE Risk for prescription opioid addiction is an endemic public health concern, especially for adults with chronic pain. This study examined craving as a mediator from pain to opioid use outcomes during prescription opioid addiction… read more here.
Keywords: pain coping; opioid use; opioid addiction; prescription opioid ... See more keywords
Examining the Effects of Celebrity (Vs. Noncelebrity) Narratives on Opioid Addiction Prevention: Identification, Transportation, and the Moderating Role of Personal Relevance
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Health Communication"
DOI: 10.1080/10810730.2022.2097752
Abstract: Celebrity disclosures and narratives are popular strategies in health promotion. However, less is known about their joint effects and the mechanisms through which they function. A 2 (narrative type: celebrity vs. layperson) x 2 (personal… read more here.
Keywords: relevance; prevention; celebrity; opioid addiction ... See more keywords
An Ultra-Brief Mindfulness-Based Intervention for Patients in Treatment for Opioid Addiction with Buprenorphine: A Primary Care Feasibility Pilot Study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of alternative and complementary medicine"
DOI: 10.1089/acm.2019.0242
Abstract: Objectives: To demonstrate the feasibility and acceptability of a brief mindfulness-based intervention taught by physicians for patients with opioid addiction and to determine if the intervention reduces likelihood of relapse or treatment failure within 6… read more here.
Keywords: mindfulness; medicine; intervention; treatment ... See more keywords
Craving Behavior from Opioid Addiction Controlled with Olanzapine in an Advanced Cancer Patient: A Case Report.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of palliative medicine"
DOI: 10.1089/jpm.2017.0636
Abstract: Opioid addiction, although uncommon in cancer patients, can be a significant challenge for optimal pain management in certain patients. We present a case of a 59-year-old man with advanced colon cancer whose compulsive craving for… read more here.
Keywords: addiction; craving behavior; opioid addiction; controlled olanzapine ... See more keywords
Glutamatergic Systems and Memory Mechanisms Underlying Opioid Addiction.
Sign Up to like & getrecommendations! Published in 2020 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a039602
Abstract: Glutamate is the main excitatory neurotransmitter in the brain and is of critical importance for the synaptic and circuit mechanisms that underlie opioid addiction. Opioid memories formed over the course of repeated drug use and… read more here.
Keywords: addiction; systems memory; glutamatergic systems; opioid addiction ... See more keywords
Genetic Vulnerability to Opioid Addiction.
Sign Up to like & getrecommendations! Published in 2020 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a039735
Abstract: Opioid addiction, also referred to as opioid use disorder, continues to be a devastating problem throughout the world. Familial relation and twin studies have revealed opioid addiction, like other addictive diseases, to be profoundly influenced… read more here.
Keywords: addiction; vulnerability opioid; genetics; opioid addiction ... See more keywords
Fentanyl vapor self-administration model in mice to study opioid addiction
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abc0413
Abstract: Fentanyl vapor self-administration in mice provides a novel and noninvasive model to study opioid addiction. Intravenous drug self-administration is considered the “gold standard” model to investigate the neurobiology of drug addiction in rodents. However, its… read more here.
Keywords: self administration; administration; fentanyl vapor; opioid addiction ... See more keywords
Vitamin D deficiency exacerbates UV/endorphin and opioid addiction
Sign Up to like & getrecommendations! Published in 2021 at "Science Advances"
DOI: 10.1126/sciadv.abe4577
Abstract: Addiction to UV light and opioids is increased by VitD deficiency, suggesting that a feedback loop promotes its synthesis. The current opioid epidemic warrants a better understanding of genetic and environmental factors that contribute to… read more here.
Keywords: addiction; vitd deficiency; opioid use; opioid addiction ... See more keywords