Interactions between opioids and cannabinoids: Economic demand for opioid/cannabinoid mixtures.
Sign Up to like & getrecommendations! Published in 2020 at "Drug and alcohol dependence"
DOI: 10.1016/j.drugalcdep.2020.108043
Abstract: BACKGROUND Opioid abuse remains a significant public health challenge. With continuing emergence of novel psychoactive substances (e.g., synthetic cannabinoids found in "K2" or "spice" preparations), the co-administration of opioids and other novel drugs is likely… read more here.
Keywords: jwh 018; cannabinoid mixtures; economic demand; opioid cannabinoid ... See more keywords
Rotenoids and Other Specialized Metabolites from the Roots of Mirabilis multiflora: Opioid and Cannabinoid Receptor Radioligand Binding Affinities.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.0c00939
Abstract: Mirabilis multiflora is an acclaimed hallucinogen consumed traditionally by the Hopi Indians to induce diagnostic visions. Its root extract afforded a new (3) and four known (2, 5, 6, and 7) 12a-hydroxyrotenoids, a known rotenoid… read more here.
Keywords: radioligand binding; binding affinities; mirabilis multiflora; receptor ... See more keywords
Crotalphine Modulates Microglia M1/M2 Phenotypes and Induces Spinal Analgesia Mediated by Opioid-Cannabinoid Systems
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911571
Abstract: Pain is a worldwide public health problem and its treatment is still a challenge since clinically available drugs do not completely reverse chronic painful states or induce undesirable effects. Crotalphine is a 14 amino acids… read more here.
Keywords: analgesia; effect; opioid cannabinoid; crotalphine ... See more keywords