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   Articles with "opioid dependence" as a keyword



The intergenerational persistence of opioid dependence: Evidence from administrative data

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recommendations! Published in 2022 at "Health Economics"

DOI: 10.1002/hec.4589

Abstract: Abstract To address the opioid crisis, it is crucial to understand its origins. We provide descriptive evidence for the intergenerational persistence of opioid dependence. Our analysis is based on administrative data covering the universe of… read more here.

Keywords: administrative data; persistence opioid; opioid dependence; intergenerational persistence ... See more keywords

Review of Case Narratives from Fatal Overdoses Associated with Injectable Naltrexone for Opioid Dependence

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recommendations! Published in 2018 at "Drug Safety"

DOI: 10.1007/s40264-018-0653-3

Abstract: IntroductionAn extended-release injectable naltrexone suspension (Vivitrol®) was approved in USA in 2010 for the prevention of relapse to opioid dependence. Concerns, raised at the time of approval, about rebound overdose risk following the last dose,… read more here.

Keywords: fatal overdoses; case narratives; injectable naltrexone; case ... See more keywords

Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans

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recommendations! Published in 2018 at "Biological Psychiatry"

DOI: 10.1016/j.biopsych.2017.12.016

Abstract: BACKGROUND Opioid dependence (OD) is at epidemic levels in the United States. Genetic studies can provide insight into its biology. METHODS We completed an OD genome-wide association study in 3058 opioid-exposed European Americans, 1290 of… read more here.

Keywords: genome wide; study; opioid dependence; rgma ... See more keywords

Initial Results From An Opioid Dependence Whole Exome Sequencing Study

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recommendations! Published in 2019 at "European Neuropsychopharmacology"

DOI: 10.1016/j.euroneuro.2017.06.056

Abstract: Abstract It is well known that the risk of opioid dependence (OD) is genetically influenced. Several GWAS, including ours, have succeeded at identifying common risk variants for OD. We undertook the present whole exome sequence… read more here.

Keywords: risk; study; opioid dependence; whole exome ... See more keywords

Current and emerging pharmacotherapies for opioid dependence treatments in adults: a comprehensive update

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recommendations! Published in 2022 at "Expert Opinion on Pharmacotherapy"

DOI: 10.1080/14656566.2022.2140039

Abstract: ABSTRACT Introduction Opioid use disorder (OUD) is characterized by compulsive opioid seeking and taking, intense drug craving, and intake of opioids despite negative consequences. The prevalence of OUDs has now reached an all-time high, in… read more here.

Keywords: emerging pharmacotherapies; pharmacotherapies opioid; opioid dependence; opioid ... See more keywords

Opioid Dependence and Overdose After Surgery

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recommendations! Published in 2022 at "Annals of Surgery"

DOI: 10.1097/sla.0000000000005546

Abstract: Objective: To determine: (1) incidence of “opioid never events” (ONEs), defined as the development of opioid dependence or overdose in an opioid-naive surgical patient who is prescribed opioids postoperatively and (2) risk factors predicting ONEs.… read more here.

Keywords: naive surgical; surgery; opioid dependence; opioid naive ... See more keywords

Time‐dependent neuronal changes associated with craving in opioid dependence: an fMRI study

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recommendations! Published in 2018 at "Addiction Biology"

DOI: 10.1111/adb.12554

Abstract: Relapse after initially successful treatment is a significant problem facing the treatment of opioid dependence. Evidence suggests craving elicited by re‐exposure to drug cues may precipitate relapse. Attempts to identify neural biomarkers of cue‐elicited craving… read more here.

Keywords: drug cue; opioid dependence; cue; time ... See more keywords

Cerebrospinal Fluid Biomarkers in Opioid Dependence: Evidence of Neuroimmune Activation and Ion Composition Changes, Without Alteration in Orexin‐A

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recommendations! Published in 2025 at "Addiction Biology"

DOI: 10.1111/adb.70053

Abstract: Opioid abuse is a severe global health challenge, leading to rising morbidity, mortality, and increasing societal costs. The aim of this study was to investigate neuroinflammation, neuronal damage and potential changes in the orexin system… read more here.

Keywords: neuroimmune activation; dependence; cerebrospinal fluid; orexin ... See more keywords

Barriers to access to opioid medicines for patients with opioid dependence: a review of legislation and regulations in eleven central and eastern European countries

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recommendations! Published in 2017 at "Addiction"

DOI: 10.1111/add.13755

Abstract: BACKGROUND AND AIMS Barriers linked to drug control systems are considered to contribute to inequitable access to controlled medicines, leaving millions of people in pain and suffering. Most studies focus on access to opioids for… read more here.

Keywords: legislation regulations; legislation; patients opioid; opioid dependence ... See more keywords

Prevalence of opioid dependence in Scotland 2015-2020: A multi-parameter estimation of prevalence (MPEP) study.

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recommendations! Published in 2024 at "Addiction"

DOI: 10.1111/add.16500

Abstract: BACKGROUND AND AIMS Drug-related deaths in Scotland more than doubled between 2011 and 2020. To inform policymakers and understand drivers of this increase, we estimated the number of people with opioid dependence aged 15-64 from… read more here.

Keywords: people opioid; prevalence opioid; opioid dependence; prevalence ... See more keywords

Provider costs of treating opioid dependence with extended‐release buprenorphine in Australia

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recommendations! Published in 2024 at "Drug and Alcohol Review"

DOI: 10.1111/dar.13956

Abstract: Abstract Introduction The costs of providing medication‐assisted treatment for opioid dependence can determine its scale of provision. To provide estimates of the costs of extended‐release buprenorphine (BUP‐XR), we performed a bottom‐up costing analysis of provider… read more here.

Keywords: treatment; release buprenorphine; extended release; cost ... See more keywords