Long-term Risk of Overdose or Mental Health Crisis After Opioid Dose Tapering
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.16726
Abstract: Key Points Question Is opioid dose tapering associated with reduced longer-term risks of overdose, withdrawal, or mental health crisis in patients prescribed long-term opioids? Findings In this cohort study of 19 377 patients, in a posttaper… read more here.
Keywords: health crisis; dose tapering; opioid dose; mental health ... See more keywords
Impact of multidisciplinary chart reviews on opioid dose reduction and monitoring practices.
Sign Up to like & getrecommendations! Published in 2018 at "Addictive behaviors"
DOI: 10.1016/j.addbeh.2018.04.018
Abstract: INTRODUCTION The Veterans Affairs (VA) Eastern Colorado Health Care System implemented an Opioid Safety Initiative (OSI); this included multidisciplinary chart reviews of patients with chronic, non-malignant pain on high-dose opioid therapy to provide safety recommendations… read more here.
Keywords: reduction; chart reviews; monitoring; opioid dose ... See more keywords
Outcomes after opioid dose reductions and stoppage: It's time to start counting.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of substance abuse treatment"
DOI: 10.1016/j.jsat.2019.05.010
Abstract: ----“We didn’t have a heroin crisis in America before OxyContin was approved and started being handed out like candy...We could fix the majority of this problem with a click of our fingers,” declared Vermont’s Governor,… read more here.
Keywords: outcomes opioid; reductions stoppage; opioid dose; time start ... See more keywords
Opioid Dose and Survival of Patients with Incurable Nonsmall Cell Lung Cancer: A Prospective Cohort Study.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of palliative medicine"
DOI: 10.1089/jpm.2018.0044
Abstract: BACKGROUND Preclinical studies show that opioids promote angiogenesis, tumor progression, and metastasis, resulting in shorter survival. OBJECTIVE To explore whether opioids are associated with the overall survival (OS) of patients with incurable nonsmall cell lung… read more here.
Keywords: incurable nonsmall; cell lung; survival patients; nonsmall cell ... See more keywords
Relationships Between Opioid Dosing, Pain Severity, and Disability in a Community-Based Chronic Pain Population: An Exploratory Retrospective Analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Pain medicine"
DOI: 10.1093/pm/pny240
Abstract: Objective To determine the relationship between opioid dose change, pain severity, and function in patients with chronic pain. Design Retrospective cohort study. Setting Community interdisciplinary pain management practice. Subjects A total of 778 patients with… read more here.
Keywords: change; disability; pain severity; opioid dose ... See more keywords
Impact of opioid dose escalation on pain intensity: a retrospective cohort study.
Sign Up to like & getrecommendations! Published in 2020 at "Pain"
DOI: 10.1097/j.pain.0000000000001784
Abstract: Prescribers are often confronted with the decision to escalate opioid doses to achieve adequate analgesia. Understanding the impact of dose escalation on pain intensity is warranted. Using a retrospective cohort study design, Veterans with chronic… read more here.
Keywords: pain intensity; dose escalation; dose maintainers; opioid dose ... See more keywords
Preoperative Opioid Dose and Surgical Outcomes in Colorectal Surgery.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American College of Surgeons"
DOI: 10.1097/xcs.0000000000000109
Abstract: BACKGROUND The worsening opioid epidemic has led to an increased number of surgical patients with chronic preoperative opioid use. However, the impact of opioids on perioperative outcomes has yet to be fully elucidated. The purpose… read more here.
Keywords: surgical outcomes; dose surgical; opioid dose; mme ... See more keywords
Randomised, pragmatic, waitlist controlled trial of cannabis added to prescription opioid support on opioid dose reduction and pain in adults with chronic non-cancer pain: study protocol
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-064457
Abstract: Introduction Chronic, non-cancer pain impacts approximately 50 million adults in the USA (20%), approximately 25% of whom receive chronic prescription opioids for pain despite limited empirical efficacy data and strong dose-related risk for opioid use disorder… read more here.
Keywords: cannabis; prescription; trial; opioid dose ... See more keywords
Impact of prehospital opioid dose on angiographic and clinical outcomes in acute coronary syndromes
Sign Up to like & getrecommendations! Published in 2022 at "Emergency Medicine Journal"
DOI: 10.1136/emermed-2021-211519
Abstract: Background An adverse interaction whereby opioids impair and delay the gastrointestinal absorption of oral P2Y12 inhibitors has been established, however the clinical significance of this in acute coronary syndrome (ACS) is uncertain. We sought to… read more here.
Keywords: clinical outcomes; prehospital opioid; acute coronary; opioid dose ... See more keywords
Prehospital opioid dose and myocardial injury in patients with ST elevation myocardial infarction
Sign Up to like & getrecommendations! Published in 2020 at "Open Heart"
DOI: 10.1136/openhrt-2020-001307
Abstract: Objective To characterise the relationship between opioid dose and myocardial infarct size in patients with ST elevation myocardial infarction (STEMI). Methods Patients given opioid treatment by emergency medical services with confirmed STEMI were included in… read more here.
Keywords: opioid dose; myocardial infarction; patients elevation; dose myocardial ... See more keywords
Impact of Early Analgesia on Hospitalization for Sickle Cell Pain Crisis
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood.v130.suppl_1.4649.4649
Abstract: National Institutes of Health guidelines for management of sickle cell acute pain suggests the use of an individualized prescribing protocol to improve outcomes for patients suffering from acute pain. The evidence that individualized pain plans… read more here.
Keywords: maximum opioid; admission; time; opioid dose ... See more keywords