Association of Prenatal Opioid Exposure With Precentral Gyrus Volume in Children.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA pediatrics"
DOI: 10.1001/jamapediatrics.2020.0937
Abstract: This cross-sectional study identifies structural differences of the precentral gyrus among children with reported prenatal opioid exposure compared with children with no reported exposure, controlling for present social factors. read more here.
Keywords: association prenatal; exposure; opioid exposure; precentral gyrus ... See more keywords
Embryonic opioid exposure impairs inhibitory transmission of striatum in day-old chicks.
Sign Up to like & getrecommendations! Published in 2022 at "Developmental psychobiology"
DOI: 10.1002/dev.22273
Abstract: Studies of humans, mammalian animals, and chicks reveal that embryonic opioid exposure (EOE) changes the response to pharmacological rewards in postnatal individuals, which may be an outcome of permanent alterations to neural systems. However, the… read more here.
Keywords: inhibitory transmission; transmission; opioid exposure; embryonic opioid ... See more keywords
A review of the literature: How does prenatal opioid exposure impact placental health and fetal brain development?
Sign Up to like & getrecommendations! Published in 2023 at "Developmental psychobiology"
DOI: 10.1002/dev.22378
Abstract: In recent years, there has been a sixfold increase in the number of pregnant people with opioid use disorder (OUD). Rates of neonatal opioid withdrawal syndrome (NOWS), previously known as neonatal abstinence syndrome (NAS), have… read more here.
Keywords: brain development; fetal brain; opioid exposure; literature ... See more keywords
Prenatal opioid exposure: The next neonatal neuroinflammatory disease
Sign Up to like & getrecommendations! Published in 2020 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2019.11.007
Abstract: The rates of opioid use disorder during pregnancy have more than quadrupled in the last decade, resulting in numerous infants suffering exposure to opioids during the perinatal period, a critical period of central nervous system… read more here.
Keywords: methadone exposure; exposure; opioid exposure; injury ... See more keywords
Management of Newborns with Prenatal Opioid Exposure: One Institution's Journey.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical therapeutics"
DOI: 10.1016/j.clinthera.2019.07.001
Abstract: The prevalence of newborns with neonatal abstinence syndrome (NAS) is rising sharply. To respond to this crisis, our institution re-examined our policies and procedures regarding our approach to the management of newborns with prenatal opioid… read more here.
Keywords: newborns prenatal; institution; opioid exposure; management newborns ... See more keywords
Review of addiction risk potential associated with adolescent opioid use
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2020.173022
Abstract: Adolescence is a critical period of development with robust behavioral, morphological, hormonal, and neurochemical changes including changes in brain regions implicated in the reinforcing effects of drugs such as opioids. Here we examine the preclinical… read more here.
Keywords: opioid use; opioid exposure; use; adolescent opioid ... See more keywords
Early life stress and environmental influences on the neurodevelopment of children with prenatal opioid exposure
Sign Up to like & getrecommendations! Published in 2018 at "Neurobiology of Stress"
DOI: 10.1016/j.ynstr.2018.08.005
Abstract: Prenatal opioid exposure has reached epidemic proportions. In the last 10 years, there has been a 242% increase in the number of babies born with the drug withdrawal syndrome known as Neonatal Opioid Withdrawal Syndrome… read more here.
Keywords: exposure; opioid exposure; early life; stress ... See more keywords
Prenatal Opioid Exposure Research: Shortcomings and Solutions.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Addiction Medicine"
DOI: 10.1097/adm.0000000000000590
Abstract: First, some studies examining the association between NAS history and infant/child outcomes report significant relationships. However, such relationships cannot be examined in isolation. It is quite likely that such findings are due in large part… read more here.
Keywords: nas history; exposure research; social determinants; prenatal opioid ... See more keywords
Prenatal Opioid Exposure and Neurodevelopmental Outcomes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurosurgical Anesthesiology"
DOI: 10.1097/ana.0000000000000876
Abstract: The opioid epidemic in the United States has resulted in a significant increase in opioid use disorder among pregnant women and a concomitant increase in the incidence of neonatal opioid withdrawal syndrome. The long-term consequences… read more here.
Keywords: prenatal opioid; exposure neurodevelopmental; neurodevelopmental outcomes; opioid exposure ... See more keywords
Concordance of opioid exposure in all-payer claims databases with prescription drug monitoring program database using Arkansas as a case example.
Sign Up to like & getrecommendations! Published in 2022 at "Health services research"
DOI: 10.1111/1475-6773.14117
Abstract: OBJECTIVE To assess the concordance between and benefit of adding prescription drug monitoring program (PDMP) data to all-payer claims database (APCD) data for identifying and classifying opioid exposure among insured individuals. DATA SOURCES AND STUDY… read more here.
Keywords: opioid exposure; pdmp; concordance; apcd pdmp ... See more keywords
Neurobehavioral effects of neonatal opioid exposure in mice: Influence of the OPRM1 SNP.
Sign Up to like & getrecommendations! Published in 2019 at "Addiction biology"
DOI: 10.1111/adb.12806
Abstract: Opioid use among pregnant women is a growing public health concern in the United States. Infants exposed to opioids in utero are at risk of exhibiting neonatal opioid withdrawal syndrome (NOWS). The biological mechanisms underlying… read more here.
Keywords: oprm1 snp; exposure; neonatal opioid; opioid exposure ... See more keywords