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   Articles with "opioid signaling" as a keyword



Synergistic regulation of serotonin and opioid signaling contributes to pain insensitivity in Nav1.7 knockout mice

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recommendations! Published in 2017 at "Science Signaling"

DOI: 10.1126/scisignal.aah4874

Abstract: The voltage-gated Na+ channel Nav1.7 controls the balance of pain-promoting and pain-relieving receptor input. Channeling pain through GPCRs Identification of Nav1.7 as responsible for the absence of pain sensitivity in humans has prompted the investigation… read more here.

Keywords: opioid signaling; nav1; mice; nav1 knockout ... See more keywords

SUN-094 Elevated opioid signaling in the arcuate nucleus dopaminergic (A12) neurons in lactating rats

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recommendations! Published in 2025 at "Journal of the Endocrine Society"

DOI: 10.1210/jendso/bvaf149.1678

Abstract: Abstract Disclosure: P. Cromb: None. D.R. Grattan: None. S. Yip: None. The arcuate nucleus (ARN) dopaminergic (A12) neurons release dopamine to inhibit prolactin secretion. During lactation, these neurons cease dopamine production, allowing prolactin levels to… read more here.

Keywords: a12 neurons; opioid signaling; opr; arcuate nucleus ... See more keywords

Integrated Single-Cell Transcriptome Analysis Reveals Novel Insights into the Role of Opioid Signaling in the Pathophysiology of Inflammatory Bowel Disease

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recommendations! Published in 2025 at "Biomedicines"

DOI: 10.3390/biomedicines13061398

Abstract: Background/Objectives: Inflammatory bowel disease (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), is characterized by chronic gastrointestinal inflammatory diseases with complex etiology and remains a therapeutic challenge due to heterogeneous treatment responses. Opioids are… read more here.

Keywords: disease; ibd; single cell; opioid signaling ... See more keywords

Novel Roles of Non-Coding RNAs in Opioid Signaling and Cardioprotection

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recommendations! Published in 2018 at "Non-Coding RNA"

DOI: 10.3390/ncrna4030022

Abstract: Cardiovascular disease (CVD) is a significant cause of morbidity and mortality across the world. A large proportion of CVD deaths are secondary to coronary artery disease (CAD) and myocardial infarction (MI). Even though prevention is… read more here.

Keywords: coding rnas; opioid signaling; novel roles; non coding ... See more keywords