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   Articles with "opioid tolerant" as a keyword



The Effectiveness of Regular Opioids for Dyspnea Among Opioid-Tolerant Patients with Cancer: A Comparison of Increasing Baseline Opioids Versus Opioid Switch/Combination Therapy

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recommendations! Published in 2025 at "Journal of Palliative Medicine"

DOI: 10.1089/jpm.2024.0487

Abstract: Background: Dyspnea is a common and distressing symptom in patients with cancer and often worsens even with the use of opioids for pain management. Understanding effective strategies for managing dyspnea in opioid-tolerant patients is essential… read more here.

Keywords: dyspnea; combination; patients cancer; tolerant patients ... See more keywords

Perioperative and Periprocedural anesthetic management of opioid tolerant patients and patients with active and medically treated opioid use disorder

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recommendations! Published in 2022 at "Current Opinion in Anaesthesiology"

DOI: 10.1097/aco.0000000000001157

Abstract: Purpose of review The increasing prevalence of opioid tolerant individuals, in combination with the expanding scope and utilization of nonoperating room anesthesia (NORA) necessitates ongoing investigation into best clinical practice for managing surgical/procedural pain in… read more here.

Keywords: tolerant patients; opioid tolerant; opioid; opioid use ... See more keywords

Duration of peripheral nerve blocks in opioid‐tolerant individuals: A study protocol

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recommendations! Published in 2024 at "Acta Anaesthesiologica Scandinavica"

DOI: 10.1111/aas.14513

Abstract: Peripheral nerve blocks effectively alleviate postoperative pain. Animal studies and human research suggest that opioid tolerance may reduce the effectiveness of local analgesics. The reduced effectiveness has been observed in opioid‐tolerant humans and animals undergoing… read more here.

Keywords: duration; nerve; nerve blocks; opioid tolerant ... See more keywords

Effect of sustained high buprenorphine plasma concentrations on fentanyl-induced respiratory depression: A placebo-controlled crossover study in healthy volunteers and opioid-tolerant patients

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recommendations! Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0256752

Abstract: Background Opioid-induced respiratory depression driven by ligand binding to mu-opioid receptors is a leading cause of opioid-related fatalities. Buprenorphine, a partial agonist, binds with high affinity to mu-opioid receptors but displays partial respiratory depression effects.… read more here.

Keywords: respiratory depression; tolerant patients; plasma concentrations; opioid tolerant ... See more keywords

Comparing the safety and efficacy of intravenous naloxone administration in opioid-naive and opioid-tolerant hospitalized oncology patients.

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recommendations! Published in 2022 at "Journal of opioid management"

DOI: 10.5055/jom.2022.0744

Abstract: OBJECTIVE To compare naloxone doses and clinical outcomes after emergency opioid reversal in opioid-naïve and opi-oid-tolerant inpatients. DESIGN Cross-sectional, retrospective chart review. SETTING Comprehensive cancer center. PATIENTS In-patients who received ≥1 dose of intravenous naloxone… read more here.

Keywords: oncology; naloxone administration; opioid tolerant;