Newborn Cry Acoustics in the Assessment of Neonatal Opioid Withdrawal Syndrome Using Machine Learning
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.38783
Abstract: Key Points Question Can newborn cry acoustics serve as an objective biobehavioral marker of neonatal opioid withdrawal syndrome (NOWS)? Findings In this cohort study of 65 neonates with and without exposure to opioids, supervised machine… read more here.
Keywords: acoustics; cry; machine learning; opioid withdrawal ... See more keywords
Recurrent Takotsubo Cardiomyopathy Associated with Opioid Withdrawal During Buprenorphine Induction.
Sign Up to like & getrecommendations! Published in 2021 at "Cardiovascular toxicology"
DOI: 10.1007/s12012-020-09624-z
Abstract: This case report describes a 65-year-old female with iatrogenic opioid use disorder for chronic lower back pain, who developed Takotsubo cardiomyopathy on multiple occasions following buprenorphine induction. This patient had three opioid transfers to buprenorphine,… read more here.
Keywords: opioid withdrawal; cardiomyopathy; buprenorphine induction; takotsubo cardiomyopathy ... See more keywords
Approach to buprenorphine use for opioid withdrawal treatment in the emergency setting
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Emergency Medicine"
DOI: 10.1016/j.ajem.2018.10.013
Abstract: Introduction: Opioid use disorder (OUD) is increasing in prevalence throughout the world, with approximately three million individuals in the United States affected. Buprenorphine is a medication designed, researched, and effectively used to assist in OUD… read more here.
Keywords: opioid withdrawal; use; treatment; emergency ... See more keywords
Differences in patient-reported and observer-rated opioid withdrawal symptom etiology, time course, and relationship to clinical outcome.
Sign Up to like & getrecommendations! Published in 2020 at "Drug and alcohol dependence"
DOI: 10.1016/j.drugalcdep.2020.108212
Abstract: Although opioid withdrawal ratings are frequently used as primary outcomes for therapeutic trials, there has been limited empirical examination of opioid withdrawal symptom onset or etiology as an outcome, and also little examination of differences… read more here.
Keywords: opioid withdrawal; etiology; withdrawal symptom; withdrawal ... See more keywords
Clinical and psychological factors associated with interdose opioid withdrawal in chronic pain population.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of substance abuse treatment"
DOI: 10.1016/j.jsat.2021.108386
Abstract: BACKGROUND The DSM-5 diagnostic criteria for Prescription Opioid-Use Disorder (POUD) have undergone some significant changes. One of the most controversial changes has been the elimination of the withdrawal symptoms criterion when opioid use is under… read more here.
Keywords: pain; moderate severe; withdrawal; factors associated ... See more keywords
Maternal opioid use disorder: Placental transcriptome analysis for neonatal opioid withdrawal syndrome.
Sign Up to like & getrecommendations! Published in 2021 at "Genomics"
DOI: 10.1016/j.ygeno.2021.08.001
Abstract: Excessive prenatal opioid exposure may lead to the development of Neonatal Opioid Withdrawal Syndrome (NOWS). RNA-seq was done on 64 formalin-fixed paraffin-embedded placental tissue samples from 32 mothers with opioid use disorder, with newborns with… read more here.
Keywords: opioid withdrawal; withdrawal syndrome; opioid use; neonatal opioid ... See more keywords
A double-blind, randomized, placebo-controlled, pilot clinical trial examining buspirone as an adjunctive medication during buprenorphine-assisted supervised opioid withdrawal.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental and clinical psychopharmacology"
DOI: 10.1037/pha0000550
Abstract: Successful management of opioid withdrawal improves long-term treatment outcomes and reduces opioid use-related morbidity and mortality. Mechanistically supported pharmacotherapeutic approaches are needed to effectively manage acute and protracted opioid withdrawal. Buspirone is a D2 antagonist… read more here.
Keywords: supervised opioid; withdrawal; double blind; buspirone ... See more keywords
The impact of depression on opioid withdrawal symptoms among smokers with opioid use disorder receiving medication-assisted opioid detoxification.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental and clinical psychopharmacology"
DOI: 10.1037/pha0000599
Abstract: Individuals with opioid use disorder (OUD) endorse high rates of combustible smoking (Zale et al., 2015) which is associated with poorer outcomes (e.g., opioid craving and lower detoxification completion rates) among individuals receiving medications for… read more here.
Keywords: opioid use; withdrawal symptoms; depression; opioid withdrawal ... See more keywords
Clinically meaningful individual differences in opioid withdrawal expression.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental and clinical psychopharmacology"
DOI: 10.1037/pha0000654.supp
Abstract: Opioid use disorder (OUD) is a significant public health concern. An individual with an OUD may experience withdrawal after stopping opioid use. There has been limited exploration of the individual differences in withdrawal expression. This… read more here.
Keywords: individual differences; withdrawal expression; withdrawal; opioid withdrawal ... See more keywords
Neonatal opioid withdrawal syndrome: a review of the science and a look toward the use of buprenorphine for affected infants
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Perinatology"
DOI: 10.1038/s41372-021-01206-3
Abstract: Neonates born to mothers taking opioids during pregnancy are at risk for neonatal opioid withdrawal syndrome (NOWS), for which there is no recognized standard approach to care. Nonpharmacologic treatment is typically used as a first-line… read more here.
Keywords: opioid withdrawal; withdrawal syndrome; use buprenorphine; neonatal opioid ... See more keywords
Is it time to replace morphine with methadone for the treatment of pain in the neonatal intensive care unit?
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Research"
DOI: 10.1038/s41390-021-01472-z
Abstract: The current prescription opioid epidemic in the USA has also resulted in a growing number of pregnant women and their fetuses being exposed to these opioids. For decades it is known that in utero exposure… read more here.
Keywords: opioid withdrawal; withdrawal syndrome; term; treatment ... See more keywords