Opisthorchis felineus genes differentially expressed under praziquantel shed light on the nature of tegument disruption and indicate the adaptive role of cGMP-dependent protein kinase
Sign Up to like & getrecommendations! Published in 2020 at "Parasitology Research"
DOI: 10.1007/s00436-020-06764-7
Abstract: Opisthorchis felineus is a trematode flatworm that parasitises mammals, including humans, and is mainly spread throughout Eastern Europe and Western Siberia. The main drug used in treatment of opisthorchiasis and other trematode and cestode infestations… read more here.
Keywords: protein; opisthorchis felineus; disruption; nature tegument ... See more keywords
Inhibition of Opisthorchis felineus glutathione-dependent prostaglandin synthase by resveratrol correlates with attenuation of cholangiocyte neoplasia in a hamster model of opisthorchiasis.
Sign Up to like & getrecommendations! Published in 2019 at "International journal for parasitology"
DOI: 10.1016/j.ijpara.2019.07.002
Abstract: Food-borne trematodiases represent major neglected parasitic diseases. Trematodes of the family Opisthorchiidae including Opisthorchis felineus, Opisthorchis viverrini and Clonorchis sinensis are ranked eigth on the global list of the 24 most prevalent food-borne parasites. Chronic… read more here.
Keywords: opisthorchis felineus; rsv; dependent prostaglandin; felineus glutathione ... See more keywords
Characteristics of liver fibrosis associated with chronic Opisthorchis felineus infection in Syrian hamsters and humans.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2019.104274
Abstract: The food-borne liver trematode Opisthorchis felineus causes severe liver damage, including fibrosis. This study shows a comparison of the characteristics between cholangiofibrosis and periductal fibrosis in infected people and in the golden hamster as an… read more here.
Keywords: opisthorchis felineus; infection; syrian hamsters; felineus infection ... See more keywords
Similarities and differences among the Opisthorchiidae liver flukes: insights from Opisthorchis felineus
Sign Up to like & getrecommendations! Published in 2022 at "Parasitology"
DOI: 10.1017/s0031182022000397
Abstract: Abstract Abstract The foodborne liver trematode Opisthorchis felineus (Rivolta, 1884) is a member of the triad of phylogenetically related epidemiologically important Opisthorchiidae trematodes, which also includes O. viverrini (Poirier, 1886) and Clonorchis sinensis (Loos, 1907).… read more here.
Keywords: opisthorchis felineus; opisthorchiidae liver; liver; similarities differences ... See more keywords
Identification of novel natural inhibitors of Opisthorchis felineus cytochrome P450 using structure-based screening and molecular dynamic simulation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2017.1392897
Abstract: Opisthorchis felineus is the etiological agent of opisthorchiasis in humans. O. felineus cytochrome P450 (OfCYP450) is an important enzyme in the parasite xenobiotic metabolism. To identify the potential anti-opisthorchid compound, we conducted a structure-based virtual… read more here.
Keywords: opisthorchis felineus; felineus cytochrome; structure based; binding energy ... See more keywords
Infection with Opisthorchis felineus induces intraepithelial neoplasia of the biliary tract in a rodent model
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DOI: 10.1093/carcin/bgx042
Abstract: The liver fluke Opisthorchis felineus is a member of the triad of epidemiologically relevant species of the trematode family Opisthorchiidae, and the causative agent of opisthorchiasis felinea over an extensive range that spans regions of… read more here.
Keywords: biliary tract; liver fluke; opisthorchis felineus; infection ... See more keywords
Pharmacokinetics of Ascending Doses of Praziquantel in Adults Infected with Opisthorchis felineus in Western Siberia, Russian Federation
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00526-22
Abstract: Opisthorchiasis due to the liver fluke Opisthorchis felineus is highly prevalent in rural regions of Western Siberia, causing severe liver and bile duct maladies. Praziquantel administered as a three-dose regimen is the only drug used… read more here.
Keywords: opisthorchis felineus; western siberia; doses praziquantel; felineus ... See more keywords
Immunogenicity and Antigenicity of Opisthorchis felineus Proteins
Sign Up to like & getrecommendations! Published in 2020 at "Advances in Animal and Veterinary Sciences"
DOI: 10.17582/journal.aavs/2020/8.9.933.939
Abstract: | Three antigenic preparations of the human liver fluke Opisthorchis felineus were analyzed and characterized by immunochemical and serological reactions. The antigenic profiles of the excretory-secretory antigen (ES-Ag) contained 21 predominant protein bands in the… read more here.
Keywords: opisthorchis felineus; bands range; immunogenicity antigenicity; felineus ... See more keywords
Jagged-1/Notch Pathway and Key Transient Markers Involved in Biliary Fibrosis during Opisthorchis felineus Infection
Sign Up to like & getrecommendations! Published in 2022 at "Tropical Medicine and Infectious Disease"
DOI: 10.3390/tropicalmed7110364
Abstract: Chronic opisthorchiasis associated with Opisthorchis felineus infection is accompanied by severe fibrotic complications. It is of high practical significance to elucidate the mechanisms of hepatic fibrosis in chronic infection dynamics. The goal of the study… read more here.
Keywords: opisthorchis felineus; notch pathway; infection; fibrosis ... See more keywords