Hypoxia signaling: Challenges and opportunities for cancer therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2021.10.002
Abstract: Hypoxia is arguably the first recognized cancer microenvironment hallmark and affects virtually all cellular populations present in tumors. During the past decades the complex adaptive cellular responses to oxygen deprivation have been largely elucidated, raising… read more here.
Keywords: hypoxia signaling; challenges opportunities; signaling challenges; hypoxia ... See more keywords
Biology of Pre-cancers and Opportunities for Cancer Interception - lesson from colorectal cancer susceptibility syndromes.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer prevention research"
DOI: 10.1158/1940-6207.capr-22-0500
Abstract: Hereditary gastrointestinal cancer is associated with molecular and neoplastic precursors which have revealed much about sporadic carcinogenesis. Therefore, an appreciation of constitutional and somatic events linked to these syndromes have provided a useful model for… read more here.
Keywords: pre cancers; cancers opportunities; biology pre; biology ... See more keywords
Death Receptors: New Opportunities in Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Acta Naturae"
DOI: 10.32607/20758251-2017-9-3-55-63
Abstract: This article offers a detailed review of the current approaches to anticancer therapy that target the death receptors of malignant cells. Here, we provide a comprehensive overview of the structure and function of death receptors… read more here.
Keywords: death; death receptors; receptors new; therapy ... See more keywords
Oxidative Drugs and microRNA: New Opportunities for Cancer Prevention
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers15010132
Abstract: Despite the impressive progress of therapies in recent years, cancer still remains the second leading cause of death in developed countries [...]. read more here.
Keywords: microrna new; drugs microrna; oxidative drugs; opportunities cancer ... See more keywords
Strategies targeting PD-L1 expression and associated opportunities for cancer combination therapy
Sign Up to like & getrecommendations! Published in 2023 at "Theranostics"
DOI: 10.7150/thno.80091
Abstract: Immunotherapy has achieved great success recently and opened a new avenue for anti-tumor treatment. Programmed cell death 1/programmed cell death ligand 1 (PD-1/PD-L1) are typical immune checkpoints that transmit coinhibitory signals, muting the host immunity.… read more here.
Keywords: combination therapy; therapy; strategies targeting; associated opportunities ... See more keywords