Opportunities and Challenges for Decentralized Clinical Trials: European Regulators’ Perspective
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2628
Abstract: Decentralized clinical trials (DCTs) have the potential to improve accessibility, diversity, and retention in clinical trials by moving trial activities to participants’ homes and local surroundings. In this study, we conducted semi‐structured interviews with 20… read more here.
Keywords: trials european; clinical trials; decentralized clinical; challenges decentralized ... See more keywords
Involvement of sialoglycans in SARS‐COV‐2 infection: Opportunities and challenges for glyco‐based inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Iubmb Life"
DOI: 10.1002/iub.2692
Abstract: Viral infections have been the causes of global pandemics, including the ongoing coronavirus disease 2019, which prompted the investigation into the infection mechanisms to find treatment and aid the vaccine design. Betacoronaviruses use spike glycoprotein… read more here.
Keywords: challenges glyco; infection; glyco based; opportunities challenges ... See more keywords
Metal-Based Electrocatalysts for Methanol Electro-Oxidation: Progress, Opportunities, and Challenges.
Sign Up to like & getrecommendations! Published in 2019 at "Small"
DOI: 10.1002/smll.201904126
Abstract: Direct methanol fuel cells (DMFCs) are among the most promising portable power supplies because of their unique advantages, including high energy density/mobility of liquid fuels, low working temperature, and low emission of pollutants. Various metal-based… read more here.
Keywords: oxidation; metal; opportunities challenges; metal based ... See more keywords
Opportunities and Challenges in Stem Cell Aging.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2021_624
Abstract: Studying aging, as a physiological process that can cause various pathological phenotypes, has attracted lots of attention due to its increasing burden and prevalence. Therefore, understanding its mechanism to find novel therapeutic alternatives for age-related… read more here.
Keywords: challenges stem; cell aging; stem cell; opportunities challenges ... See more keywords
Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7465-8_13
Abstract: From the pharmacological point of view, allosteric modulators may present numerous advantages over orthosteric ligands. Growing availability of novel tools and experimental data provides a tempting opportunity to apply computational methods to improve known modulators… read more here.
Keywords: modulators gpcrs; challenges discovery; allosteric modulators; opportunities challenges ... See more keywords
Computational Opportunities and Challenges in Finding Cyclic Peptide Modulators of Protein-Protein Interactions.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9504-2_5
Abstract: Peptide cyclization can improve stability, conformational constraint, and compactness. However, apart from beta-turn structures, which are well incorporated into cyclic peptides (CPs), many primary peptide structures and functions are markedly altered by cyclization. Accordingly, to… read more here.
Keywords: peptide; cyclic peptide; opportunities challenges; computational opportunities ... See more keywords
The rise of ward monitoring: opportunities and challenges for critical care specialists
Sign Up to like & getrecommendations! Published in 2018 at "Intensive Care Medicine"
DOI: 10.1007/s00134-018-5384-5
Abstract: Introduction Many hospitals have implemented rapid response teams (RRTs) for rescue interventions outside the ICU. The outcome impact of RRTs is still a matter of debate but there is a consensus regarding the fact that… read more here.
Keywords: rise ward; ward monitoring; opportunities challenges; monitoring ... See more keywords
Opportunities, challenges, and future perspectives of succinic acid production by Actinobacillus succinogenes
Sign Up to like & getrecommendations! Published in 2018 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-018-9379-5
Abstract: Due to environmental issues and the depletion of fossil-based resources, ecofriendly sustainable biomass-based chemical production has been given more attention recently. Succinic acid (SA) is one of the top value added bio-based chemicals. It can… read more here.
Keywords: succinic acid; production; actinobacillus succinogenes; future perspectives ... See more keywords
Data Plane Programmability Beyond OpenFlow: Opportunities and Challenges for Network and Service Operations and Management
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Network and Systems Management"
DOI: 10.1007/s10922-017-9423-2
Abstract: SDN and OpenFlow reshaped the way we configure forwarding devices and determine network behavior, by offering an open interface upon which apps like routing, monitoring, etc. can be built. SDN/OpenFlow helped break network “ossification” and… read more here.
Keywords: plane programmability; network; network service; management ... See more keywords
Multi-Objective Optimization in WSN: Opportunities and Challenges
Sign Up to like & getrecommendations! Published in 2021 at "Wireless Personal Communications"
DOI: 10.1007/s11277-021-08627-5
Abstract: Wireless sensor networks (WSNs) plays a significant role in the field of surveillance, monitoring the real time applications. Regardless its strong ability to handle such tasks, it is difficult to maintain a trade-off between the… read more here.
Keywords: wsn opportunities; multi objective; objective optimization; opportunities challenges ... See more keywords
Biobanking in amphibian and reptilian conservation and management: opportunities and challenges
Sign Up to like & getrecommendations! Published in 2020 at "Conservation Genetics Resources"
DOI: 10.1007/s12686-020-01142-y
Abstract: Numerous species from the classes Amphibia and Reptilia are facing extinction as a result of habitat loss and increasing anthropogenic impact on the environment; to be more specific, 32% amphibian and 20% reptilian species are… read more here.
Keywords: amphibian reptilian; conservation management; conservation; opportunities challenges ... See more keywords