Enantioselective Dearomative Alkynylation of Chromanones: Opportunities and Obstacles
Sign Up to like & getrecommendations! Published in 2022 at "Synthesis"
DOI: 10.1055/a-1811-8075
Abstract: A catalytic and highly enantioselective dearomative alkynylation of chromanones has been discovered that enables the construction of biologically relevant tertiary ether stereogenic centers. This methodology is robust, accommodating a variety of alkynes and chromanones. More… read more here.
Keywords: alkynylation chromanones; enantioselective dearomative; opportunities obstacles; dearomative alkynylation ... See more keywords
Clinical chemoproteomics—Opportunities and obstacles
Sign Up to like & getrecommendations! Published in 2017 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aaf7951
Abstract: The prospects for applying chemoproteomics in the clinical setting are discussed. Chemoproteomics is the large-scale study of proteins using chemical methods. Although chemoproteomic techniques are becoming commonplace in preclinical research, few examples have found clinical… read more here.
Keywords: clinical chemoproteomics; chemoproteomics opportunities; medicine; opportunities obstacles ... See more keywords