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Published in 2019 at "Climate Dynamics"
DOI: 10.1007/s00382-019-04786-1
Abstract: We investigate the opposing effects of direct radiative forcing and sea surface warming on the atmospheric circulation using a hierarchy of models. In large ensembles of three general circulation models, direct $$\hbox {CO}_2$$CO2 forcing produces…
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Keywords:
surface warming;
sea;
opposing effects;
sea surface ... See more keywords
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1
Published in 2018 at "Developmental cell"
DOI: 10.1016/j.devcel.2018.02.012
Abstract: Recurrent mutations in chromatin modifiers are specifically prevalent in adolescent or adult patients with Sonic hedgehog-associated medulloblastoma (SHH MB). Here, we report that mutations in the acetyltransferase CREBBP have opposing effects during the development of…
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Keywords:
adult;
crebbp mutations;
opposing effects;
rubinstein taybi ... See more keywords
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1
Published in 2019 at "Acta Physiologica"
DOI: 10.1111/apha.13269
Abstract: Loss of skeletal muscle is one of the main features of cancer cachexia. Vitamin D (VD) deficiency is associated with impairment of muscle mass and performance and is highly prevalent in cachectic patients; therefore, VD…
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Keywords:
effects hydroxy;
muscle;
dihydroxy vitamin;
hydroxy dihydroxy ... See more keywords
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2
Published in 2022 at "Blood advances"
DOI: 10.1182/blood-2022-170403
Abstract: Glucocorticoids (GCs) are a cornerstone of acute lymphoblastic leukemia (ALL) therapy. While mutations in NR3C1, which encodes the GC receptor (GR), and other genes involved in GC signaling occur at relapse, additional mechanisms of adaptive…
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Keywords:
opposing effects;
jdp2 expression;
sensitivity;
expression ... See more keywords
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1
Published in 2021 at "European journal of endocrinology"
DOI: 10.1530/eje-20-1123
Abstract: OBJECTIVE The association between dysregulated thyroid hormone function and cancer risk is inconclusive, especially among different age groups and uncommon malignancies. We sought to determine the relation of TSH and free T4 levels with overall…
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Keywords:
effects thyroid;
opposing effects;
cancer;
risk ... See more keywords
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1
Published in 2017 at "Critical reviews in oncogenesis"
DOI: 10.1615/critrevoncog.2017020882
Abstract: In this review, we introduce a new vision of cancer describing opposing effects that control progression. Cancer is a paradigm of opposing of "Yin" and "Yang," with Yin being the effect to promote cancer and…
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Keywords:
cancer;
opposing effects;
progression;
yin yang ... See more keywords
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2
Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032311
Abstract: Trained immunity is the process of long-term functional reprogramming (a de facto innate immune memory) of innate immune cells such as monocytes and macrophages after an exposure to pathogens, vaccines, or their ligands. The induction…
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Keywords:
opposing effects;
interleukin interleukin;
effects interleukin;
immunity ... See more keywords