Outcomes after salvage for HPV-positive recurrent oropharyngeal cancer treated with primary radiation.
Sign Up to like & getrecommendations! Published in 2020 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2020.105125
Abstract: PURPOSE HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) carries a favorable prognosis for patients, yet nearly 30% of patients will experience disease relapse. We sought to detail patterns of failure, associated salvage therapy, and outcomes for… read more here.
Keywords: year; site; recurrent hpv; hpv positive ... See more keywords
Elevated TLR5 expression in vivo and loss of NF-κΒ activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2020.104435
Abstract: In oropharyngeal squamous cell carcinoma (OPSCC), the expression pattern of toll-like receptors (TLRs), in comparison between human papillomavirus (HPV)-positive and -negative tumors differs. TLRs control innate immune responses by activating, among others, the nuclear factor-κΒ… read more here.
Keywords: cell; hpv negative; opscc; tlr5 expression ... See more keywords
Human papillomavirus and oral and oropharyngeal carcinoma: the essentials
Sign Up to like & getrecommendations! Published in 2019 at "Australian Dental Journal"
DOI: 10.1111/adj.12652
Abstract: There is a global increase in the prevalence of human papillomavirus (HPV)-driven oropharyngeal squamous cell carcinoma (OPSCC) in Australia and New Zealand. Risk factors for HPV-positive OPSCC are male gender, white race, age older than… read more here.
Keywords: carcinoma; positive opscc; hpv; human papillomavirus ... See more keywords
Abstract 41: Proteomic stratification of HPV(+) oropharyngeal squamous cell carcinoma identifies targets in insulin receptor signaling within nonresponders
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.aacrahns17-41
Abstract: Objective: The global rise of HPV(+) oropharyngeal squamous cell carcinoma (OPSCC) has generated considerable interest underlying its etiology and management. Relative to HPV(-) OPSCC, HPV(+) patients are younger and more responsive to chemoradiation, though non-responders… read more here.
Keywords: squamous cell; hpv; hpv oropharyngeal; cell ... See more keywords
Abstract A07: Improved prognosis of HPV-positive oropharyngeal cancers is associated with a suppression of TGF-β-mediated immune evasion
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.aacrahns19-a07
Abstract: Among head and neck squamous carcinoma (HNSC), human papilloma virus (HPV)-driven tumors are known to enjoy more favorable prognostic outcomes compared to non-HPV-driven disease. This is especially true of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC),… read more here.
Keywords: positive oropharyngeal; prognosis; hpv positive; hnsc ... See more keywords
Aptima HR-HPV Testing of Cytology Specimens Is an Effective Supplement for p16 Staining to Improve Diagnostic Accuracy for HPV-Related Oropharyngeal Squamous Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Acta cytologica"
DOI: 10.1159/000527951
Abstract: INTRODUCTION Regarding a small proportion of oropharyngeal squamous cell carcinoma (OPSCC) patients who tested p16-positive but human papillomavirus (HPV)-negative, we attempted to perform HPV testing to improve the accuracy of HPV detection in OPSCC patients.… read more here.
Keywords: aptima hpv; hpv testing; opscc; p16 ... See more keywords
Discrepancy in p16 expression in patients with HPV-associated head and neck squamous cell carcinoma in Thailand: clinical characteristics and survival outcomes
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DOI: 10.1186/s12885-021-08213-9
Abstract: Background Lower prevalence HPV infection has been previously reported in Thai population when compared with Western countries. p16 expression indicates HPV-associated oropharyngeal squamous cell carcinoma (OPSCC), but not non-OPSCC. We therefore evaluated the characteristic and… read more here.
Keywords: non opscc; p16 expression; hpv associated; opscc non ... See more keywords
BEST OF: A phase III study assessing the best of radiotherapy (Intensity Modulated RadioTherapy, IMRT) compared to the best of surgery (Trans-Oral Surgery, TOS) in patients with T1-T2, N0 oropharyngeal squamous cell carcinoma (OPSCC).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.tps6098
Abstract: TPS6098Background: The incidence of OPSCC has increased dramatically in the last 15 years. The standard treatment for early stage disease is either surgery or radiotherapy, both with comparable hig... read more here.
Keywords: best phase; surgery; radiotherapy; phase iii ... See more keywords
Understanding the impact of high-risk human papillomavirus on oropharyngeal squamous cell carcinomas in Taiwan: A retrospective cohort study
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DOI: 10.1371/journal.pone.0250530
Abstract: Background and objectives Human papillomavirus (HPV)-driven oropharyngeal squamous cell carcinoma (OPSCC) is increasing globally. In Taiwan, HPV-positive OPSCC is obscured by tobacco, alcohol, and betel quid use. We investigated the role of high-risk HPV (hrHPV)… read more here.
Keywords: risk; hpv; human papillomavirus; hpv positive ... See more keywords
Transoral Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma of the Tonsil versus Base of Tongue: A Systematic Review and Meta-Analysis
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DOI: 10.3390/cancers14153837
Abstract: Simple Summary Transoral Robotic Surgery (TORS) has become widely adopted for the surgical removal of oropharyngeal squamous cell carcinoma (OPSCC). However, it is currently unknown if TORS has equal efficacy and outcomes in patients with… read more here.
Keywords: opscc; tonsillar opscc; positive margins; rate ... See more keywords
Association of Suppressive Myeloid Cell Enrichment with Aggressive Oropharynx Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15082346
Abstract: Simple Summary Human papillomavirus positive (HPV+) ororpharyngeal squamous cell carcinoma (OPSCC) patients have improved clinical prognosis, compared to HPV-negative OPSCC patients. While HPV+ OPSCC patients often have more immune-cell-infiltrated tumors, they can be subjected to… read more here.
Keywords: hpv negative; cell; opscc; squamous cell ... See more keywords