High-performance microbial opsins for spatially and temporally precise perturbations of large neuronal networks
Sign Up to like & getrecommendations! Published in 2022 at "Neuron"
DOI: 10.1016/j.neuron.2022.01.008
Abstract: The biophysical properties of existing optogenetic tools constrain the scale, speed, and fidelity of precise optogenetic control. Here, we use structure-guided mutagenesis to engineer opsins that exhibit very high potency while retaining fast kinetics. These… read more here.
Keywords: high performance; microbial opsins; opsins spatially; performance microbial ... See more keywords