Analysis of Pregnancy-Related Attacks in Neuromyelitis Optica Spectrum Disorder
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.25438
Abstract: Key Points Question What are the factors associated with pregnancy-related attacks in neuromyelitis optica spectrum disorder? Findings This systematic review and meta-analysis of 15 studies with 443 patients found that receiving immunosuppressive treatment during pregnancy… read more here.
Keywords: neuromyelitis optica; optica spectrum; pregnancy related; spectrum disorder ... See more keywords
Effects of pregnancy on neuromyelitis optica spectrum disorder and predictors of related attacks
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51683
Abstract: Our study aimed to investigate the influence of pregnancy on the course of neuromyelitis optica spectrum disorders (NMOSD) and to explore the independent predictors of pregnancy‐related attacks. read more here.
Keywords: neuromyelitis optica; effects pregnancy; optica spectrum; pregnancy neuromyelitis ... See more keywords
Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202500942
Abstract: Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disease characterized by anti‐aquaporin 4 (AQP4) antibody‐mediated astrocyte damage and subsequent demyelination. Prior attempts to treat NMOSD with interferon‐beta (IFN‐β), a disease‐modifying therapy for multiple sclerosis, resulted… read more here.
Keywords: optica spectrum; neuromyelitis optica; interferon; spectrum disorder ... See more keywords
Serum Glial Fibrillary Acidic Protein: A Neuromyelitis Optica Spectrum Disorder Biomarker
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Neurology"
DOI: 10.1002/ana.26067
Abstract: Blood tests to monitor disease activity, attack severity, or treatment impact in neuromyelitis optica spectrum disorder (NMOSD) have not been developed. This study investigated the relationship between serum glial fibrillary acidic protein (sGFAP) concentration and… read more here.
Keywords: serum glial; spectrum disorder; fibrillary acidic; neuromyelitis optica ... See more keywords
Aquaporin‐4 Antibody Dynamics and Relapse Risk in Seropositive Neuromyelitis Optica Spectrum Disorder Treated with Immunosuppressants
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Neurology"
DOI: 10.1002/ana.26623
Abstract: To investigate aquaporin‐4 antibody (AQP4‐IgG) dynamics and relapse risk in patients with seropositive neuromyelitis optica spectrum disorder treated with immunosuppressants. read more here.
Keywords: neuromyelitis optica; seropositive neuromyelitis; optica spectrum; aquaporin antibody ... See more keywords
Ravulizumab in Aquaporin‐4–Positive Neuromyelitis Optica Spectrum Disorder
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Neurology"
DOI: 10.1002/ana.26626
Abstract: CHAMPION‐NMOSD (NCT04201262) is a phase 3, open‐label, externally controlled interventional study evaluating the efficacy and safety of the terminal complement inhibitor ravulizumab in adult patients with anti–aquaporin‐4 antibody–positive (AQP4+) neuromyelitis optica spectrum disorder (NMOSD). Ravulizumab… read more here.
Keywords: neuromyelitis optica; spectrum disorder; ravulizumab; optica spectrum ... See more keywords
Elevated cerebrospinal fluid uric acid during relapse of neuromyelitis optica spectrum disorders
Sign Up to like & getrecommendations! Published in 2017 at "Brain and Behavior"
DOI: 10.1002/brb3.584
Abstract: Previous studies have shown that serum uric acid (UA) modulates outcomes of neurological diseases, although little is known about cerebrospinal fluid (CSF) UA levels in neuromyelitis optica spectrum disorders (NMOSDs). read more here.
Keywords: uric acid; spectrum disorders; neuromyelitis optica; optica spectrum ... See more keywords
Evaluation of CD3+CD56+ NKT and CD19+ B Cells in Assessing the Relapse of Neuromyelitis Optica Spectrum Disorder Patients Treated With Rituximab
Sign Up to like & getrecommendations! Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70950
Abstract: The purpose of this study was to explore the value of pre‐treatment levels of CD3+CD56+ NKT cells and CD19+ B cells in evaluating the relapse of patients with neuromyelitis optica spectrum disorders (NMOSD) treated with… read more here.
Keywords: cd19 cells; neuromyelitis optica; treated rituximab; optica spectrum ... See more keywords
Remyelination in neuromyelitis optica spectrum disorder is promoted by edaravone through mTORC1 signaling activation
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24271
Abstract: Neuromyelitis optica spectrum disorder (NMOSD) is a severe inflammatory autoimmune disease of the central nervous system that is manifested as secondary myelin loss. Oligodendrocyte progenitor cells (OPCs) are the principal source of myelinating oligodendrocytes (OLs)… read more here.
Keywords: neuromyelitis optica; remyelination; mtorc1 signaling; optica spectrum ... See more keywords
Differential brainstem atrophy patterns in multiple sclerosis and neuromyelitis optica spectrum disorders
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25866
Abstract: Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are central nervous system (CNS) inflammatory demyelinating disorders. It is clinically important to distinguish MS from NMOSD, as treatment and prognosis differ. Brainstem involvement is common… read more here.
Keywords: spectrum disorders; neuromyelitis optica; multiple sclerosis; optica spectrum ... See more keywords
Quantitative radiomic biomarkers for discrimination between neuromyelitis optica spectrum disorder and multiple sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.26287
Abstract: Precise diagnosis and early appropriate treatment are of importance to reduce neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) morbidity. Distinguishing NMOSD from MS based on clinical manifestations and neuroimaging remains challenging. read more here.
Keywords: neuromyelitis optica; multiple sclerosis; spectrum disorder; optica spectrum ... See more keywords