FSOCA-induced switchable footpad skin optical clearing window for blood flow and cell imaging in vivo.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biophotonics"
DOI: 10.1002/jbio.201700052
Abstract: The mouse footpad for its feature of hairlessness provides an available window for imaging vascular and cellular structure and function in vivo. Unfortunately, the strong scattering of its skin limits the penetration of light and reduces… read more here.
Keywords: blood flow; window; optical clearing; blood ... See more keywords
In vivo monitoring blood-brain barrier permeability using spectral imaging through optical clearing skull window.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biophotonics"
DOI: 10.1002/jbio.201800330
Abstract: The blood-brain barrier (BBB) plays a key role in the health of the central nervous system. Opening the BBB is very important for drug delivery to brain tissues to enhance the therapeutic effect on brain… read more here.
Keywords: skull window; optical clearing; brain; clearing skull ... See more keywords
Integrated effects of fractional laser microablation and sonophoresis on skin immersion optical clearing in vivo.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biophotonics"
DOI: 10.1002/jbio.202000101
Abstract: This study is aimed to find an approach for effective skin optical clearing in vivo using polyethylene glycol 300 (PEG-300) as an optical clearing agent in combination with physical enhancers: fractional laser microablation (FLMA), and/or… read more here.
Keywords: sonophoresis; laser microablation; optical clearing; fractional laser ... See more keywords
Immersion optical clearing of adipose tissue in rats: ex vivo and in vivo studies
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202100393
Abstract: Optical clearing (OC) of adipose tissue has not been studied enough, although it can be promising in medical applications, including surgery and cosmetology, for example, to visualize blood vessels or increase the permeability of tissues… read more here.
Keywords: adipose tissue; clearing adipose; optical clearing; vivo studies ... See more keywords
Broadband spectral verification of optical clearing reversibility in lung tissue
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202200185
Abstract: The increase of tissue transparency through sequential optical immersion clearing treatments and treatment reversibility have high interest for clinical applications. To evaluate the clearing reversibility in a broad spectral range and the magnitude of the… read more here.
Keywords: reversibility; lung; optical clearing; treatment ... See more keywords
Characterization of optical clearing mechanisms in muscle during treatment with glycerol and gadobutrol solutions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202200205
Abstract: The recent increasing interest in the application of radiology contrasting agents to create transparency in biological tissues implies that the diffusion properties of those agents need evaluation. The comparison of those properties with the ones… read more here.
Keywords: glycerol; optical clearing; glycerol gadobutrol; muscle ... See more keywords
Dissolving Microneedle Patches Integrating Optical Clearing and Photothermal Agents for Improved Photothermal Disinfection
Sign Up to like & getrecommendations! Published in 2025 at "Macromolecular Bioscience"
DOI: 10.1002/mabi.202500158
Abstract: Photothermal disinfection is an emerging and efficient therapeutic method for treating various infections. However, the therapeutic efficacy is hindered by the poor tissue penetration of light. While tissue optical clearance technology can enhance light transmission,… read more here.
Keywords: clearing; photothermal agents; dissolving microneedle; optical clearing ... See more keywords
MR and fluorescence imaging of gadobutrol‐induced optical clearing of red fluorescent protein signal in an in vivo cancer model
Sign Up to like & getrecommendations! Published in 2022 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4708
Abstract: Multimodality registration of optical and MR images in the same tissue volume in vivo may be enabled by MR contrast agents with an optical clearing (OC) effect. The goals of this study were to (a)… read more here.
Keywords: red fluorescent; vivo; gadobutrol; tumor ... See more keywords
Tissue Optical Clearing for Biomedical Imaging: From In Vitro to In Vivo.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-7627-0_11
Abstract: Tissue optical clearing technique provides a prospective solution for the application of advanced optical methods in life sciences. This chapter firstly gives a brief introduction to mechanisms of tissue optical clearing techniques, from the physical… read more here.
Keywords: clearing methods; vitro vivo; optical clearing; tissue optical ... See more keywords
RTF: a rapid and versatile tissue optical clearing method
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-20306-3
Abstract: Tissue optical clearing enables imaging deeper in large volumes with high-resolution. ClearT2 is a relatively rapid clearing method with no use of solvents or detergents, hence poses great advantage on preservation of diverse fluorescent labels.… read more here.
Keywords: clearing method; optical clearing; rapid versatile; method ... See more keywords
ClearSeeAlpha: Advanced Optical Clearing for Whole-Plant Imaging
Sign Up to like & getrecommendations! Published in 2021 at "Plant and Cell Physiology"
DOI: 10.1093/pcp/pcab033
Abstract: Abstract To understand how the body of plants is made, it is essential to observe the morphology, structure and arrangement of constituent cells. However, the opaque nature of the plant body makes it difficult to… read more here.
Keywords: advanced optical; clearseealpha advanced; plant; whole plant ... See more keywords