L-Lactate oxidase-mediated removal of L-lactic acid derived from fermentation medium for the production of optically pure D-lactic acid.
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology journal"
DOI: 10.1002/biot.202100331
Abstract: BACKGROUND There has been an increasing demand for optically pure D-lactic and L-lactic acid for the production of stereocomplex-type polylactic acid. The D-lactic acid production from lignocellulosic biomass is important owing to its great abundance… read more here.
Keywords: pure lactic; lactic acid; optically pure; acid ... See more keywords
A Bi‐Enzymatic Cascade Pathway towards Optically Pure FAHFAs **
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202100070
Abstract: Recently discovered endogenous mammalian lipids, fatty acid esters of hydroxy fatty acids (FAHFAs), have been proved to have anti‐inflammatory and anti‐diabetic effects. Due to their extremely low abundancies in vivo, forging a feasible scenario for FAHFA… read more here.
Keywords: pathway towards; fatty acids; cascade pathway; enzymatic cascade ... See more keywords
Comparative investigation of the inclusion preferences of optically pure versus racemic TADDOL hosts for pyridine and isomeric methylpyridine guests
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.03.049
Abstract: Abstract Here we consider the effect of the optical purity of TADDOL (α,α,α′,α’-tetraphenyl-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol) on its discriminatory behaviour. We synthesized optically pure and racemic TADDOL, which form complexes with pyridine and the methylpyridines, and recrystallized them… read more here.
Keywords: methylpyridine methylpyridine; methylpyridine; comparative investigation; optically pure ... See more keywords
Optically Pure Metallohelices That Accumulate in Cell Nuclei, Condense/Aggregate DNA, and Inhibit Activities of DNA Processing Enzymes.
Sign Up to like & getrecommendations! Published in 2020 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.0c00092
Abstract: The water-compatible optically pure metallohelices made by self-assembly of simple nonpeptidic organic components around Fe(II) ions are now recognized as a distinct subclass of helicates that exhibit similar architecture to some natural cationic antimicrobial peptides.… read more here.
Keywords: condense aggregate; dna; aggregate dna; optically pure ... See more keywords
Stereoselective Synthesis of Optically Pure 2-Amino-2'-hydroxy-1,1'-binaphthyls.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00800
Abstract: Direct entry to optically pure 2-amino-2'-hydroxy-1,1'-binaphthyl (NOBIN) derivatives by an iron-catalyzed stereoselective oxidative cross-coupling reaction between 2-naphthol and 2-aminonaphthalene with a labile chiral auxiliary is reported. This efficient method offers entry to tailor-designed ( R… read more here.
Keywords: optically pure; pure amino; stereoselective synthesis; amino hydroxy ... See more keywords
(1S)-(−)-N-Trifluoromethylthio-2,10-camphorsultam and its derivatives: easily available, optically pure reagents for asymmetric trifluoromethylthiolation
Sign Up to like & getrecommendations! Published in 2017 at "Organic chemistry frontiers"
DOI: 10.1039/c7qo00042a
Abstract: A family of easily scalable, shelf-stable, optically pure reagents (1S)-(−)-N-trifluoromethylthio-2,10-camphorsultam 1a–c was successfully developed. In particular, compound 1c was shown to be an efficient reagent that is capable of transferring chirality to other prochiral nucleophiles… read more here.
Keywords: trifluoromethylthio camphorsultam; camphorsultam derivatives; derivatives easily; easily available ... See more keywords
Chiron approach towards optically pure γ-valerolactone from alanine
Sign Up to like & getrecommendations! Published in 2018 at "Synthetic Communications"
DOI: 10.1080/00397911.2018.1491993
Abstract: Abstract A concise synthesis of both enantiomers of γ-valerolactone has been developed from commercially available Alanine. The key steps in the synthesis of these γ-Lactones are DIBAL-H reduction of ester (9) followed by in situ… read more here.
Keywords: approach towards; valerolactone alanine; chiron approach; towards optically ... See more keywords
Boron Tetrafluoride Anion Bonding Dual Active Species Within a Large–Pore Mesoporous Silica for Two–Step Successive Organic Transformaion to Prepare Optically Pure Amino Alcohols
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2018.00272
Abstract: Development of a simple and easy handing process for preparation of multifunctional heterogenous catalysts and exploration of their applications in sequential organic transformation are of great significance in heterogeneous asymmetric catalysis. Herein, through the utilization… read more here.
Keywords: secondary amino; amino; anion bonding; amino alcohols ... See more keywords
Water-Soluble Ruthenium (II) Complex Derived From Optically Pure Limonene and Its Microencapsulation Are Efficient Tools Against Bacterial Food Pathogen Biofilms: Escherichia coli, Staphylococcus aureus, Enteroccocus faecalis, and Listeria monocytogenes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.711326
Abstract: Bioactive aminooxime ligands based on optically pure (R)-limonene have been synthesized in two steps. Their ruthenium (II) cationic water-soluble complex was prepared by a reaction between dichloro (para-cymene) ruthenium (II) dimers and aminooxime ligands in… read more here.
Keywords: optically pure; complex; ruthenium complex; water soluble ... See more keywords
Elucidating a Complicated Enantioselective Metabolic Profile: A Study From Rats to Humans Using Optically Pure Doxazosin
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.834897
Abstract: Doxazosin (DOX) is prescribed as a racemic drug for the clinical treatment of benign prostatic hyperplasia and hypertension. Recent studies found that the two enantiomers of DOX exhibit differences in blood concentration and pharmacological effects.… read more here.
Keywords: metabolites dox; enantioselective metabolic; metabolic; optically pure ... See more keywords
Concise Synthesis of Catechin Metabolites 5-(3′,4′-Dihydroxyphenyl)-γ-valerolactones (DHPV) in Optically Pure Form and Their Stereochemical Effects on Skin Wrinkle-Reducing Activities
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25081970
Abstract: A concise and scalable synthetic route for optically pure (4S) and (4R)-5-(3′,4′-dihydroxyphenyl)-γ-valerolactones (DHPVs), catechin metabolites, has been developed via the efficient construction of a γ-valerolactone moiety from hexenol. Noticeably, the different skin wrinkle-reducing activities of… read more here.
Keywords: wrinkle reducing; skin wrinkle; catechin metabolites; dihydroxyphenyl valerolactones ... See more keywords