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   Articles with "optimal dosing" as a keyword



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Salinity-dependent pharmacokinetics of florfenicol in Nile tilapia (Oreochromis niloticus) and its implication in optimal dosing regimen

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recommendations! Published in 2020 at "Aquaculture"

DOI: 10.1016/j.aquaculture.2019.734900

Abstract: Abstract Nile tilapia has been cultured in a wide salinity range, from freshwater to up to 15 ppt brackish water due to its euryhaline characteristics. As salinity profoundly affects the physiology of freshwater and seawater fish… read more here.

Keywords: salinity dependent; optimal dosing; salinity; florfenicol nile ... See more keywords
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Socially optimal dosing for scarce vaccines: Ethical analysis through the principlism framework.

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recommendations! Published in 2023 at "Journal of evaluation in clinical practice"

DOI: 10.1111/jep.13850

Abstract: RATIONALE, AIMS, AND OBJECTIVES Under conditions of vaccine scarcity, the socially optimal dosing (SOD) strategy administers a lower dose of vaccine to a larger number of people than the individually optimal dosing (IOD) strategy, which… read more here.

Keywords: principlism; socially optimal; scarce vaccines; sod ... See more keywords
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Optimal dosing of zoledronate to prevent fractures: improving risk‐benefit balance

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recommendations! Published in 2019 at "Journal of Internal Medicine"

DOI: 10.1111/joim.12915

Abstract: In their prospective, randomized, placebo-controlled, double-blind trial that investigated anti-fracture efficacy of zoledronate in a total of 2000 osteopenic postmenopausal women aged over 65 years, Reid et al. [1, 2] provides crucial evidence that is highly… read more here.

Keywords: optimal dosing; risk; zoledronate; dosing zoledronate ... See more keywords
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P109 Optimal dosing regimen of caspofungin in children: milligram per kilogram or milligram per square meter?

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recommendations! Published in 2019 at "Archives of Disease in Childhood"

DOI: 10.1136/archdischild-2019-esdppp.147

Abstract: Background Caspofungin is the first echinocandin to be used as a first-line antifungal agent for Candida spp. infections in febrile, neutropenic adult and paediatric patients. To date, the optimal dosing of capofungin in children has… read more here.

Keywords: optimal dosing; p109 optimal; milligram per; population ... See more keywords
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OPTIMAL DOSING STRATEGIES AGAINST SUSCEPTIBLE AND RESISTANT BACTERIA

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recommendations! Published in 2018 at "Journal of Biological Systems"

DOI: 10.1142/s0218339018500031

Abstract: Mathematical models can be very useful in determining efficient and successful antibiotic dosing techniques against bacterial infections. There are several challenging issues involved, the presence of drug resistant bacteria being one. Recent rise in antibiotic… read more here.

Keywords: optimal dosing; susceptible resistant; dosing strategies; resistant bacteria ... See more keywords

Prediction of the Optimal Dosing Regimen Using a Mathematical Model of Tumor Uptake for Immunocytokine-Based Cancer Immunotherapy

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recommendations! Published in 2018 at "Clinical Cancer Research"

DOI: 10.1158/1078-0432.ccr-17-2953

Abstract: Purpose: Optimal dosing is critical for immunocytokine-based cancer immunotherapy to maximize efficacy and minimize toxicity. Cergutuzumab amunaleukin (CEA-IL2v) is a novel CEA-targeted immunocytokine. We set out to develop a mathematical model to predict intratumoral CEA-IL2v… read more here.

Keywords: optimal dosing; model; cancer; cea il2v ... See more keywords