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Published in 2021 at "Journal of the American Statistical Association"
DOI: 10.1080/01621459.2020.1745814
Abstract: Abstract There is an extensive literature on the estimation and evaluation of optimal individualized treatment rules in settings where all confounders of the effect of treatment on outcome are observed. We study the development of…
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Keywords:
optimal individualized;
decision rules;
treatment;
individualized decision ... See more keywords
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Published in 2018 at "Biometrics"
DOI: 10.1111/biom.12743
Abstract: Precision medicine seeks to provide treatment only if, when, to whom, and at the dose it is needed. Thus, precision medicine is a vehicle by which healthcare can be made both more effective and efficient.…
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Keywords:
individualized treatment;
medicine;
optimal individualized;
treatment rules ... See more keywords
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Published in 2020 at "Biometrics"
DOI: 10.1111/biom.13406
Abstract: Optimal individualized treatment rules (ITRs) provide customized treatment recommendations based on subject characteristics to maximize clinical benefit in accordance with the objectives in precision medicine. As a result, there is growing interest in developing statistical…
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Keywords:
individualized treatment;
optimal individualized;
treatment;
estimating optimal ... See more keywords
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Published in 2022 at "Biometrics"
DOI: 10.1111/biom.13864
Abstract: Multistate process data are common in studies of chronic diseases such as cancer. These data are ideal for precision medicine purposes as they can be leveraged to improve more refined health outcomes, compared to standard…
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Keywords:
individualized treatment;
methodology;
estimating optimal;
treatment rules ... See more keywords