Discovering optimal kinetic pathways for self-assembly using automatic differentiation
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DOI: 10.1073/pnas.2403384121
Abstract: Significance Self-assembly of protein subunits into macromolecular complexes is ubiquitous and essential for living systems. A common obstacle during self-assembly is the formation of kinetically trapped intermediates that dramatically reduce functional yield. We show here… read more here.
Keywords: optimal kinetic; automatic differentiation; self assembly; self ... See more keywords