A general statistic to test an optimally weighted combination of common and/or rare variants
Sign Up to like & getrecommendations! Published in 2019 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22255
Abstract: Both genome‐wide association study and next‐generation sequencing data analyses are widely employed to identify disease susceptible common and/or rare genetic variants. Rare variants generally have large effects though they are hard to detect due to… read more here.
Keywords: optimally weighted; common rare; rare variants; test ... See more keywords
Optimal Sample Acquisition for Optimally Weighted PCA From Heterogeneous Quality Sources
Sign Up to like & getrecommendations! Published in 2025 at "IEEE Signal Processing Letters"
DOI: 10.1109/lsp.2025.3550280
Abstract: Modern high-dimensional datasets are often formed by acquiring samples from multiple sources having heterogeneous quality, i.e., some sources are noisier than others. Collecting data in this manner raises the following natural question: what is the… read more here.
Keywords: optimal sample; optimally weighted; quality sources; weighted pca ... See more keywords