Articles with "optimisation novel" as a keyword



Crashworthiness analysis and multi-objective optimisation of a novel circular tube under three-point bending

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Published in 2021 at "International Journal of Crashworthiness"

DOI: 10.1080/13588265.2021.1926860

Abstract: A new excellent energy absorption structure named as leaf vein branched circular tubes (LVBCT) is proposed based on lotus leaf vein branched structure. The crashworthiness of LVBCT under lateral lo... read more here.

Keywords: analysis multi; multi objective; crashworthiness analysis; objective optimisation ... See more keywords
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Optimisation of novel small molecule inhibitors of SRPK1‐mediated VEGF‐A splicing through modelling of permeability properties required for trans‐scleral eye drop delivery

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Published in 2017 at "Acta Ophthalmologica"

DOI: 10.1111/j.1755-3768.2017.02612

Abstract: Purpose Development of non-invasive therapies for wAMD and DME has not yet been successful due to poor PK/PD properties. SRPK1 is a novel target that controls VEGF-A splicing. Delivery of potent small molecules to the… read more here.

Keywords: vegf splicing; delivery; permeability; eye ... See more keywords