Articles with "optimization chitosan" as a keyword



Microfluidic platform for synthesis and optimization of chitosan-coated magnetic nanoparticles in cisplatin delivery.

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Published in 2021 at "Carbohydrate polymers"

DOI: 10.1016/j.carbpol.2021.118027

Abstract: In this study, magnetic core/chitosan shell Nanoparticles (NPs) containing cisplatin were synthesized via cisplatin complexation with tripolyphosphate as the chitosan crosslinker using two different procedures: a conventional batch flow method and a microfluidic approach. An… read more here.

Keywords: synthesis optimization; platform synthesis; microfluidic platform; delivery ... See more keywords

Development and Optimization of Chitosan-Ascorbate-Based Mucoadhesive Films for Buccal Delivery of Captopril

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Published in 2025 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics17040401

Abstract: Background: Captopril (CAP), an angiotensin-converting enzyme inhibitor (ACEI), is widely prescribed for managing hypertension, heart failure, and related conditions. When administered orally, CAP undergoes hepatic metabolism, resulting in a bioavailability of 60–75%. However, to bypass… read more here.

Keywords: mucoadhesive films; optimization chitosan; delivery; chitosan ascorbate ... See more keywords