Articles with "optimization crispr" as a keyword



Optimization of CRISPR/Cas9 genome editing for loss-of-function in the early chick embryo.

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Published in 2017 at "Developmental biology"

DOI: 10.1016/j.ydbio.2017.08.036

Abstract: The advent of CRISPR/Cas9 has made genome editing possible in virtually any organism, including those not previously amenable to genetic manipulations. Here, we present an optimization of CRISPR/Cas9 for application to early avian embryos with… read more here.

Keywords: genome editing; optimization crispr; crispr cas9; cas9 ... See more keywords
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Optimization of CRISPR/LbCas12a-mediated gene editing in Arabidopsis

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0265114

Abstract: CRISPR/LbCas12a system (LbCpf1) has been widely used for genome modification including plant species. However, the efficiency of CRISPR/LbCas12a varied considerably in different plant species and tissues, and the editing efficiency needs to be further improved.… read more here.

Keywords: editing efficiency; crispr; efficiency crispr; crispr lbcas12a ... See more keywords