Optimization and evaluation of mucoadhesive buccal films loaded with resveratrol
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2017.12.007
Abstract: Abstract Resveratrol, a phytoalexin from grapes, has shown several therapeutic benefits such as anti-inflammatory and chemopreventive effects. There is a need to develop novel methods for delivery of resveratrol since it poses problems such as… read more here.
Keywords: evaluation mucoadhesive; optimization evaluation; buccal films; mucoadhesive buccal ... See more keywords
Synthesis, Optimization, and Evaluation of Glycosylated Naphthalimide Derivatives as Efficient and Selective Insect β- N-Acetylhexosaminidase OfHex1 Inhibitors.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b02281
Abstract: Insect chitinolytic β- N-acetylhexosaminidase OfHex1, from the agricultural pest Ostrinia furnacalis (Guenée), is considered as a potential target for green pesticide design. In this study, rational molecular design and optimization led to the synthesis of… read more here.
Keywords: evaluation glycosylated; optimization evaluation; synthesis optimization; acetylhexosaminidase ofhex1 ... See more keywords
Optimization and Evaluation of Novel Antifungal Agents for the Treatment of Fungal Infection.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01299
Abstract: Due to the increased morbidity and mortality by fungal infections and the emergence of severe antifungal resistance, there is an urgent need for new antifungal agents. Here, we screened for antifungal activity in our in-house… read more here.
Keywords: novel antifungal; antifungal agents; evaluation novel; optimization evaluation ... See more keywords
Discovery, Optimization, and Evaluation of Novel ANGPTL3 Modulators for the Treatment of Hyperlipidemia.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.5c00732
Abstract: Angiopoietin-like protein 3 (ANGPTL3) has emerged as an attractive therapeutic target for treating hyperlipidemia. Evinacumab, a monoclonal antibody targeting ANGPTL3, was approved by the FDA for homozygous familial hypercholesterolemia in 2021. Here, a series of… read more here.
Keywords: optimization evaluation; angptl3 modulators; discovery optimization; novel angptl3 ... See more keywords
Discovery, Optimization, and Evaluation of Non-Nucleoside SARS-CoV-2 NSP14 Inhibitors.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.5c01155
Abstract: We recently reported the discovery of TDI-015051, a first-in-class small-molecule inhibitor of the SARS-CoV-2 guanine-N7 methyltransferase nonstructural protein 14 (NSP14). NSP14 plays a critical role in viral RNA cap synthesis and its inhibition represents a… read more here.
Keywords: sars cov; optimization evaluation; cov nsp14; non nucleoside ... See more keywords
Optimization and Evaluation of Stabilizers for Tight Water-Sensitive Conglomerate Reservoirs
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c06140
Abstract: The upper Wuerhe formation in the Mahu-1 play is a tight conglomerate reservoir that has characteristics of low porosity and low permeability. During the early stage of field development, it has been noticed that horizontal… read more here.
Keywords: water sensitive; rock; optimization evaluation; water ... See more keywords
Multi-objective optimization evaluation of renewable and clean methanol synthesis
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Low-Carbon Technologies"
DOI: 10.1093/ijlct/ctae295
Abstract: This study examines the feasibility of establishing a power-to-fuel facility for synthesizing renewable methanol (e-methanol) through the integration of green hydrogen and captured carbon dioxide. Hydrogen is produced via water electrolysis using surplus renewable electricity,… read more here.
Keywords: multi objective; optimization evaluation; methanol; objective optimization ... See more keywords
Retracted: Optimization and Evaluation of an Intelligent Short-Term Blood Glucose Prediction Model Based on Noninvasive Monitoring and Deep Learning Techniques
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Healthcare Engineering"
DOI: 10.1155/2023/9832729
Abstract: [This retracts the article DOI: 10.1155/2022/8956850.]. read more here.
Keywords: optimization evaluation; evaluation intelligent; retracted optimization; term blood ... See more keywords