Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
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DOI: 10.1021/acschembio.8b00701
Abstract: DJ-1 is a Parkinson's disease associated protein endowed with enzymatic, redox sensing, regulatory, chaperoning, and neuroprotective activities. Although DJ-1 has been vigorously studied for the past decade and a half, its exact role in the… read more here.
Keywords: associated protein; discovery optimization; optimization inhibitors; disease ... See more keywords