Discovery and Optimization of LATS1 and LATS2 Kinase Inhibitors for Use in Regenerative Medicine
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DOI: 10.1021/acs.jmedchem.5c01027
Abstract: The Large Tumor Suppressor Kinases 1 and 2 (LATS1/2) are serine/threonine kinases that play an essential role in Hippo pathway activation and influence multiple physiological events ranging from organ growth to tissue regeneration. As a… read more here.
Keywords: discovery optimization; optimization lats1; medicine; lats1 lats2 ... See more keywords