Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors.
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DOI: 10.1021/acs.jmedchem.2c00611
Abstract: With over 200 million cases and close to half a million deaths each year, malaria is a threat to global health, particularly in developing countries. Plasmodium falciparum, the parasite that causes the most severe form… read more here.
Keywords: design synthesis; macrocyclic peptides; species selective; proteasome inhibitors ... See more keywords